G C Shore

Biochemistry, Genetics and Molecular Biology · Life Sciences

33h-index4.2kcitations58works0.02yr avg
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Research Topics

Mitochondrial Function and Pathology(24), Metabolism and Genetic Disorders(14), Cell death mechanisms and regulation(9), Virus-based gene therapy research(9), ATP Synthase and ATPases Research(6)

Publications58 total

DZ-2384 tubulin complex
2016
Bcl-2-associated autophagy regulator Naf-1 required for maintenance of skeletal muscle
Human Molecular Genetics·2012· 111 citedOpen Access
Small-Molecule Bcl-2 Antagonists as Targeted Therapy in Oncology
Current Oncology·2008· 20 citedOpen Access
Chemical genomics and molecular medicine
Genomic Medicine·2008Open Access
The endoplasmic reticulum in apoptosis and autophagy: role of the BCL-2 protein family
Oncogene·2008· 262 cited
470 POSTER Target identification permits rational development of the prodrug GMX1777 for the treatment of melanoma
European Journal of Cancer Supplements·2008· 1 cited
BCL-2 phosphorylation modulates sensitivity to the BH3 mimetic GX15-070 (Obatoclax) and reduces its synergistic interaction with bortezomib in chronic lymphocytic leukemia cells
Leukemia·2008· 81 cited
Regulated targeting of Bax and Bak to intracellular membranes during apoptosis
Cell Death and Differentiation·2006· 25 cited
Cellular Distribution of Bcl-2 Family Proteins
Science Signaling·2003· 12 cited
A Conceptual Model of Child Psychopathology: Implications for Understanding Attention Deficit Hyperactivity Disorder and Treatment Efficacy
Journal of Clinical Child & Adolescent Psychology·2001· 192 cited
BID-dependent and BID-independent pathways for BAX insertion into mitochondria
Cell Death and Differentiation·2000· 107 citedOpen Access
Upgrading the Science and Technology of Assessment and Diagnosis: Laboratory and Clinic-Based Assessment of Children With ADHD
Journal of Clinical Child Psychology·2000· 114 cited
Regulated Targeting of Proteins to Mitochondria During Apoptosis
Biochemical Society Transactions·2000
E4orf4, a Novel Adenovirus Death Factor That Induces p53-independent Apoptosis by a Pathway That Is Not Inhibited by zVAD-fmk
The Journal of Cell Biology·1998· 211 citedOpen Access
Expression of p53 in Saos-2 osteosarcoma cells induces apoptosis which can be inhibited by Bcl-2 or the adenovirus E1B-55 kDa protein.
PubMed·1996· 56 cited
Adenovirus type 5 early region 4 is responsible for E1A-induced p53-independent apoptosis
Journal of Virology·1996· 86 citedOpen Access
The human mitochondrial import receptor, hTom20p, prevents a cryptic matrix targeting sequence from gaining access to the protein translocation machinery.
The Journal of Cell Biology·1996· 22 citedOpen Access
Bcl-2 and adenovirus E1B 19 kDA protein prevent E1A-induced processing of CPP32 and cleavage of poly(ADP-ribose) polymerase.
PubMed·1996· 143 cited
Adenovirus E1A proteins induce apoptosis by both p53-dependent and p53-independent mechanisms.
PubMed·1995· 127 cited
A gene-type-specific enhancer regulates the carbamyl phosphate synthetase I promoter by cooperating with the proximal GAG activating element
Nucleic Acids Research·1995· 16 cited
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Frequent Co-authors

Mai Nguyen(8), Philip E. Branton(5), C Argan(5), Douglas G. Millar(4), Mai-Huong Nguyen(4), William P. Sheffield(4), Jose G. Teodoro(4), Ing Swie Goping(4), S J Korsmeyer(3), Richard Marcellus(3), C J Lusty(3), Yves Raymond(3), K. B. Freeman(3), Ilona S. Skerjanc(3), John R. Silvius(3), A.W. Bell(3), Hannah M. Heath-Engel(2), Natasha C. Chang(2), Mark D. Rapport(2), Kyong‐Mee Chung(2)