Grace H. Johnston

Institute for Musculoskeletal Health — Australia

Neuroscience · Life Sciences

11h-index660citations14works0.02yr avg
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Research Topics

Neurotransmitter Receptor Influence on Behavior(5), Asymmetric Synthesis and Catalysis(3), Circadian rhythm and melatonin(3), Chemical synthesis and alkaloids(3), Synthesis and Biological Evaluation(3)

Publications14 total

ChemInform Abstract: Heterocyclic Cycloalkanol Ethylamines as Norepinephrine Reuptake Inhibitors.
ChemInform·2010
Discovery of WAY-260022, a Potent and Selective Inhibitor of the Norepinephrine Transporter
ACS Medicinal Chemistry Letters·2010· 2 cited
Heterocyclic cycloalkanol ethylamines as norepinephrine reuptake inhibitors
Bioorganic & Medicinal Chemistry Letters·2010· 8 citedOpen Access
1-(Indolin-1-yl)-1-phenyl-3-propan-2-olamines as Potent and Selective Norepinephrine Reuptake Inhibitors
Journal of Medicinal Chemistry·2010· 24 citedOpen Access
Dual acting norepinephrine reuptake inhibitors and 5-HT2A receptor antagonists: Identification, synthesis and activity of novel 4-aminoethyl-3-(phenylsulfonyl)-1H-indoles
Bioorganic & Medicinal Chemistry·2009· 33 citedOpen Access
Structure–activity relationships of the 1-amino-3-(1H-indol-1-yl)-3-phenylpropan-2-ol series of monoamine reuptake inhibitors
Bioorganic & Medicinal Chemistry Letters·2009· 15 citedOpen Access
3-(Arylamino)-3-phenylpropan-2-olamines as a new series of dual norepinephrine and serotonin reuptake inhibitors
Bioorganic & Medicinal Chemistry Letters·2009· 19 citedOpen Access
Synthesis and activity of novel 1- or 3-(3-amino-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones as selective norepinephrine reuptake inhibitors
Bioorganic & Medicinal Chemistry Letters·2008· 15 citedOpen Access
Synthesis and activity of 1-(3-amino-1-phenylpropyl)indolin-2-ones: A new class of selective norepinephrine reuptake inhibitors
Bioorganic & Medicinal Chemistry Letters·2008· 12 citedOpen Access
Structure−Activity Relationships of the Cycloalkanol Ethylamine Scaffold: Discovery of Selective Norepinephrine Reuptake Inhibitors
Journal of Medicinal Chemistry·2008· 23 citedOpen Access
Subchronic 17α-ethinyl estradiol differentially affects subtypes of sleep and wakefulness in ovariectomized rats
Hormones and Behavior·2007· 14 cited
Alleviation of Thermoregulatory Dysfunction with the New Serotonin and Norepinephrine Reuptake Inhibitor Desvenlafaxine Succinate in Ovariectomized Rodent Models
Endocrinology·2006· 59 citedOpen Access
Desvenlafaxine Succinate: A New Serotonin and Norepinephrine Reuptake Inhibitor
Journal of Pharmacology and Experimental Therapeutics·2006· 377 citedOpen Access
Serotonin 2A receptors modulate tail-skin temperature in two rodent models of estrogen deficiency-related thermoregulatory dysfunction
Brain Research·2004· 59 cited

Frequent Co-authors

Darlene C. Deecher(14), Paige E. Mahaney(10), Eugene J. Trybulski(10), Jenifer A. Bray(9), Scott Cosmi(9), Kevin D. Burroughs(6), A. T. Vu(6), Peter D. Alfinito(5), Elizabeth J. Koury(5), Stephen T. Cohn(5), Puwen Zhang(5), Jennifer Leiter(5), Liza Leventhal(4), Douglas M. Ho(4), Christine Huselton(3), Joseph P. Sabatucci(3), Yingru Zhang(3), Eugene A. Terefenko(3), Richard C. Winneker(2), Gavin D. Heffernan(2)