Pamela J. Holland

Centre for Inflammation Research — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index454citations15works9.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Receptor Mechanisms and Signaling(9), Neurotransmitter Receptor Influence on Behavior(4), Neuroscience and Neuropharmacology Research(3), Ion channel regulation and function(3), Neuropeptides and Animal Physiology(3)

Publications15 total

3062 – PLATELETS SEQUESTER EXTRACELLULAR DNA, CAPTURING TUMOR-DERIVED AND FREE FETAL DNA
Experimental Hematology·2025
Platelets sequester extracellular DNA, capturing tumor-derived and free fetal DNA
Science·2025· 18 citedOpen Access
Platelets Sequester Extracellular DNA, Capturing Tumour-Derived and Free Fetal DNA
Blood·2023· 4 cited
Potential Oncogenic Effect of the MERTK-Dependent Apoptotic-Cell Clearance Pathway in Starry-Sky B-Cell Lymphoma
Frontiers in Immunology·2020· 11 citedOpen Access
The TRPM8 channel forms a complex with the 5-HT1B receptor and phospholipase D that amplifies its reversal of pain hypersensitivity
Neuropharmacology·2013· 31 citedOpen Access
Attenuated PLD1 association and signalling at the H452Y polymorphic form of the 5-HT2A receptor
Cellular Signalling·2013· 5 citedOpen Access
5-HT2A receptor signalling through phospholipase D1 associated with its C-terminal tail
Biochemical Journal·2011· 19 citedOpen Access
Role of the conserved NPxxY motif of the 5-HT2A receptor in determining selective interaction with isoforms of ADP-Ribosylation Factor (ARF)
Cellular Signalling·2006· 29 cited
Selective Interaction of ARF1 with the Carboxy-Terminal Tail Domain of the 5-HT2A Receptor
Molecular Pharmacology·2003· 65 cited
ADP-ribosylation Factor-dependent Phospholipase D Activation by the M3 Muscarinic Receptor
Journal of Biological Chemistry·2003· 57 citedOpen Access
Functional interactions between native Gs-coupled 5-HT receptors in HEK-293 cells and the heterologously expressed serotonin transporter
Cellular Signalling·2003· 12 cited
ADP-Ribosylation Factor-Dependent Phospholipase D Activation by VPAC Receptors and a PAC<sub>1</sub>Receptor Splice Variant
Molecular Pharmacology·2001· 57 cited
Mechanisms of Phospholipase C Activation by the Vasoactive Intestinal Polypeptide/Pituitary Adenylate Cyclase-Activating Polypeptide Type 2 Receptor
Endocrinology·2001· 49 cited
Gonadotropin-Releasing Hormone Receptor Activation of Extracellular Signal-Regulated Kinase and Tyrosine Kinases in Transfected GH3 Cells and in αT3–1 Cells<sup>1</sup>
Endocrinology·2000· 13 citedOpen Access
The Functional Microdomain in Transmembrane Helices 2 and 7 Regulates Expression, Activation, and Coupling Pathways of the Gonadotropin-releasing Hormone Receptor
Journal of Biological Chemistry·1999· 84 citedOpen Access

Frequent Co-authors

Rory Mitchell(11), Melanie S. Johnson(10), Derek N. Robertson(9), E.M. Lutz(9), Liting Sun(3), Roberta Rosie(3), Sue Fleetwood‐Walker(3), Lauren C. Murphy(3), Jeanne Inchauspé(3), Giampiero Valenzano(3), Hayley L. Belnoue-Davis(3), Natalie J. Jooss(3), Sujata Biswas(3), Michael P. Rimmer(3), Abdullah O. Khan(3), Christina Simoglou Karali(3), Nadia Nasreddin(3), Ian S. Hitchcock(3), Milka Koupenova(3), Manu Vatish(3)