Xiao-Jiang Li

Key Laboratory of Guangdong Province — China

Neuroscience · Life Sciences

11h-index2.6kcitations18works1.52yr avg
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Research Topics

Genetic Neurodegenerative Diseases(11), Mitochondrial Function and Pathology(10), Muscle Physiology and Disorders(5), Neurological disorders and treatments(3), Genetic and Kidney Cyst Diseases(2)

Publications18 total

Tea varieties modulate rhizosphere microbiome assembly via root metabolite-mediated selection
Rhizosphere·2025
Mutant THAP11 causes cerebellar neurodegeneration and triggers TREM2-mediated microglial activation in mice
Journal of Clinical Investigation·2025· 3 citedOpen Access
Differential development and electrophysiological activity in cultured cortical neurons from the mouse and cynomolgus monkey
Neural Regeneration Research·2021· 10 citedOpen Access
Characterization of novel <i>Chrysosporium morrisgordonii</i> sp. nov., from bat white-nose syndrome (WNS) affected mines, northeastern United States
2019Open Access
Mutant Ahi1 Affects Retinal Axon Projection in Zebrafish via Toxic Gain of Function
Frontiers in Cellular Neuroscience·2019· 9 citedOpen Access
Therapeutic Effect of Berberine on Huntington’s Disease Transgenic Mouse Model
PLoS ONE·2015· 117 citedOpen Access
Loss of Ahi1 Affects Early Development by Impairing BM88/Cend1-Mediated Neuronal Differentiation
Journal of Neuroscience·2013· 40 citedOpen Access
Lack of interleukin-1 type 1 receptor enhances the accumulation of mutant huntingtin in the striatum and exacerbates the neurological phenotypes of Huntington's disease mice
Molecular Brain·2010· 6 citedOpen Access
Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms
Proceedings of the National Academy of Sciences·2009· 353 citedOpen Access
Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the SH3 domain of human AHI1
Acta Crystallographica Section F Structural Biology and Crystallization Communications·2009· 2 citedOpen Access
Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease
Human Molecular Genetics·2008· 160 citedOpen Access
Towards a transgenic model of Huntington’s disease in a non-human primate
Nature·2008· 504 citedOpen Access
Welcome to Molecular Brain
Molecular Brain·2008· 22 citedOpen Access
Mutant Huntingtin: Nuclear translocation and cytotoxicity mediated by GAPDH
Proceedings of the National Academy of Sciences·2006· 122 citedOpen Access
Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice
Proceedings of the National Academy of Sciences·2003· 422 citedOpen Access
Inhibition of Polyglutamine Aggregation in R6/2 HD Brain Slices—Complex Dose–Response Profiles
Neurobiology of Disease·2001· 70 citedOpen Access
Interaction of Huntingtin-Associated Protein with Dynactin P150<sup>Glued</sup>
Journal of Neuroscience·1998· 269 citedOpen Access
Widespread expression of Huntington's disease gene (IT15) protein product
Neuron·1995· 514 citedOpen Access

Frequent Co-authors

Shihua Li(7), Shihua Li(3), Chuan-En Wang(3), Christopher A. Ross(2), Shang‐Hsun Yang(2), Anthony W.S. Chan(2), Michael R. Hayden(2), Marta A. Gaertig(2), Sen Yan(2), Alan H. Sharp(1), Scott J. Loev(1), Gabriele Schilling(1), Jun Bao(1), Molly V. Wagster(1), Joyce A. Kotzuk(1), Joseph Steiner(1), Acy Lo(1), John C. Hedreen(1), Sangram S. Sisodia(1), Solomon H. Snyder(1)