Robin Clark

Biochemistry, Genetics and Molecular Biology · Life Sciences

26h-index4.5kcitations39works0.02yr avg
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Research Topics

Protein Kinase Regulation and GTPase Signaling(8), Virus-based gene therapy research(5), Monoclonal and Polyclonal Antibodies Research(5), Viral Infectious Diseases and Gene Expression in Insects(5), Cancer-related Molecular Pathways(4)

Publications39 total

Conformational Control Inhibition of the BCR-ABL1 Tyrosine Kinase, Including the Gatekeeper T315I Mutant, by the Switch-Control Inhibitor DCC-2036
Cancer Cell·2011· 204 citedOpen Access
Switch control pocket inhibitors of p38-MAP kinase. Durable type II inhibitors that do not require binding into the canonical ATP hinge region
Bioorganic & Medicinal Chemistry Letters·2010· 34 citedOpen Access
Analysis of Expressed Sequence Tags from Calcifying Cells of Marine Coccolithophorid (Emiliania huxleyi)
Marine Biotechnology·2004· 55 cited
RAD51C Interacts with RAD51B and Is Central to a Larger Protein Complex in Vivo Exclusive of RAD51
Journal of Biological Chemistry·2002· 88 citedOpen Access
High-throughput crystallization and structure determination in drug discovery
Drug Discovery Today·2002· 56 cited
From genes to proteins: High-throughput expression and purification of the human proteome
Journal of Cellular Biochemistry·2000· 80 cited
[2] Purification of baculovirus-expressed recombinant ras and rap proteins
Methods in enzymology on CD-ROM/Methods in enzymology·1995· 30 cited
Reconstitution of the Raf-1-MEK-ERK Signal Transduction Pathway In Vitro
Molecular and Cellular Biology·1993· 56 cited
Differential Regulation of Cellular Activities by GTPase-Activating Protein and NF1
Molecular and Cellular Biology·1993· 6 cited
Localization of the raplGAP Catalytic Domain and Sites of Phosphorylation by Mutational Analysis
Molecular and Cellular Biology·1992· 11 cited
Molecular cloning and nucleic acid binding properties of the GAP-associated tyrosine phosphoprotein p62
Cell·1992· 267 cited
Mutational and Kinetic Analyses of the GTPase-Activating Protein (GAP)-p21 Interaction: The C-Terminal Domain of GAP Is Not Sufficient for Full Activity
Molecular and Cellular Biology·1992· 49 cited
Somatic mutations in the neurofibromatosis 1 gene in human tumors
Cell·1992· 402 cited
Gap Domains Responsible for Ras P21-Dependent Inhibition of Muscarinic Atrial K <sup>+</sup> Channel Currents
Science·1992· 149 cited
Activation of BPV-1 replication in vitro by the transcription factor E2
Nature·1991· 282 cited
Identity of BCA200 and c-erbB-2 indicated by reactivity of monoclonal antibodies with recombinant c-erbB-2
Molecular Immunology·1991· 27 cited
Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1
Cell·1991· 242 cited
Targeting the E1 Replication Protein to the Papillomavirus Origin of Replication by Complex Formation with the E2 Transactivator
Science·1990· 392 cited
The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21
Cell·1990· 993 cited
Molecular Cloning and Expression of a G25K cDNA, the Human Homolog of the Yeast Cell Cycle Gene <i>CDC42</i>
Molecular and Cellular Biology·1990· 35 cited
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Frequent Co-authors

Frank McCormick(15), Leah Conroy(6), Paul Polakis(5), D. V. Sangar(4), Gideon Bollag(3), Walter J. Crosier(3), Michael A. Innis(3), Bonnee Rubinfeld(3), Eva M. Valverius(3), Martha R. Stampfer(3), David J. Rowlands(3), B. R. Rabin(3), George A. Martin(2), Peter C. McCabe(2), Richard Cawthon(2), Ian Mohr(2), Michael R. Botchan(2), Gail A. Wong(2), Matthias Frech(2), Jacob John(2)