Paul Wentworth

Scripps Research Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

33h-index4.4kcitations119works0.02yr avg
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Research Topics

Chemical Synthesis and Analysis(31), Monoclonal and Polyclonal Antibodies Research(29), Click Chemistry and Applications(13), Alzheimer's disease research and treatments(12), Glycosylation and Glycoproteins Research(12)

Publications119 total

Synthetic 1‐Deoxynojirimycin N‐Substituted Peptides Offer Prolonged Disruption to N‐Linked Glycan Processing
ChemMedChem·2014· 3 cited
Protein Misfolding and Disease
Chemical biology·2012· 1 cited
A Chemical Approach for Cell-Specific Targeting of Nanomaterials: Small-Molecule-Initiated Misfolding of Nanoparticle Corona Proteins
Journal of the American Chemical Society·2012· 114 cited
Structural biology of IgG Fc glycoforms
2012
Cholesterol Secosterol Aldehydes Induce Amyloidogenesis and Dysfunction of Wild-Type Tumor Protein p53
Chemistry & Biology·2011· 41 cited
The influence of different lipid environments on the structure and function of the hepatitis C virus p7 ion channel protein
Molecular Membrane Biology·2011· 24 cited
The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1
Nucleic Acids Research·2011· 39 citedOpen Access
Adduction of Cholesterol 5,6-Secosterol Aldehyde to Membrane-Bound Myelin Basic Protein Exposes an Immunodominant Epitope
Biochemistry·2011· 34 citedOpen Access
A shotgun proteomic study of the protein corona associated with cholesterol and atheronal-B surface-modified quantum dots
European Journal of Pharmaceutics and Biopharmaceutics·2011· 24 cited
Role of Oxidative Stress in Protein Misfolding and/or Amyloid Formation
2010· 1 cited
Cholesterol Secosterol Adduction Inhibits the Misfolding of a Mutant Prion Protein Fragment that Induces Neurodegeneration
Angewandte Chemie International Edition·2009· 12 citedOpen Access
Cholesterol Secosterol Adduction Inhibits the Misfolding of a Mutant Prion Protein Fragment that Induces Neurodegeneration
Angewandte Chemie·2009
The 3-dimensional structure of a hepatitis C virus p7 ion channel by electron microscopy
Proceedings of the National Academy of Sciences·2009· 144 citedOpen Access
Cover Picture: A Chemical Approach to Immunoprotein Engineering: Chemoselective Functionalization of Thioester Proteins in Their Native State (ChemBioChem 8/2009)
ChemBioChem·2009
A Chemical Approach to Immunoprotein Engineering: Chemoselective Functionalization of Thioester Proteins in Their Native State
ChemBioChem·2009· 6 cited
The Natural Products Beauveriolide I and III: a New Class of β‐Amyloid‐Lowering Compounds
ChemBioChem·2009· 19 citedOpen Access
The ratio of cholesterol 5,6-secosterols formed from ozone and singlet oxygen offers insight into the oxidation of cholesterol in vivo
Chemical Communications·2009· 31 citedOpen Access
Protein Misfolding and Disease
Wiley Encyclopedia of Chemical Biology·2008
Lipid-Derived Aldehydes Accelerate Light Chain Amyloid and Amorphous Aggregation
Biochemistry·2008· 41 cited
Cholesterol <i>seco</i>‐Sterol‐Induced Aggregation of Methylated Amyloid‐β Peptides—Insights into Aldehyde‐Initiated Fibrillization of Amyloid‐β
Angewandte Chemie International Edition·2008· 24 citedOpen Access
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Frequent Co-authors

Kim D. Janda(24), Anita D. Wentworth(15), Richard A. Lerner(14), Jorge J. Nieva(9), Albert Eschenmoser(7), Cindy Takeuchi(5), Anita Datta(5), Xueyong Zhu(4), Ian A. Wilson(4), Bernard Babior(3), Qinghai Zhang(3), Evan T. Powers(3), Jeffery W. Kelly(3), Lyn H. Jones(3), Raymond A. Dwek(3), Nicole Zitzmann(3), Asher Shafton(3), Rajesh K. Grover(3), Johanna C. Scheinost(3), J M Ruedi(2)