Akihiro Hino

Fujifilm (Japan) — Japan

Medicine · Health Sciences

11h-index504citations35works0.02yr avg
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Research Topics

Cardiac electrophysiology and arrhythmias(19), Ion channel regulation and function(14), Cardiac Arrhythmias and Treatments(5), Cardiac Ischemia and Reperfusion(4), Heart Failure Treatment and Management(3)

Publications35 total

Preclinical Characterization of the Radioimmunoconjugate<sup>111</sup>In or<sup>90</sup>Y-FF-21101 Against a P-Cadherin–Expressing Tumor in a Mouse Xenograft Model and a Nonhuman Primate
Journal of Nuclear Medicine·2020· 7 citedOpen Access
Zn Complex of Diaminedithiol Tetradentate Ligand as a Stable Precursor for 99mTc-Labeled Compounds
Molecules·2020· 4 citedOpen Access
C-terminal–modified LY2510924: a versatile scaffold for targeting C-X-C chemokine receptor type 4
Scientific Reports·2019· 14 citedOpen Access
Addition of a β1-Blocker to Milrinone Treatment Improves Cardiac Function in Patients with Acute Heart Failure and Rapid Atrial Fibrillation
Cardiology·2019· 11 cited
Correction of impaired calmodulin binding to RyR2 as a novel therapy for lethal arrhythmia in the pressure-overloaded heart failure
Heart Rhythm·2016· 29 cited
Recombinant Atrial Natriuretic Peptide Prevents Aberrant Ca2+ Leakage through the Ryanodine Receptor by Suppressing Mitochondrial Reactive Oxygen Species Production Induced by Isoproterenol in Failing Cardiomyocytes
PLoS ONE·2016· 11 citedOpen Access
Abstract 13700: High Affinity CaM, but Not Normal Affinity CaM Can Prevent Arrhythmias in CPVT Which Mutation is Located at CaM-like Domain of RyR2
Circulation·2015
Abstract 14991: Dantrolene Cannot Inhibit Aberrant Ca <sup>2+</sup> Release and Arrhythmias Without Calmodulin in Pressure Overload Heart Failure
Circulation·2015
Abstract 13816: Dantrolene Enhances Binding of Calmodulin to RyR2 in CPVT Which Mutation Located at Central Domain but Does Not Enhance That in CPVT With Mutation at CaM-like Domain
Circulation·2015
Tolvaptan Retains Proportion of Body Fluid Compartments during Treatment of Decompensated Heart Failure: Two Case Reports
Journal of Cardiac Failure·2015Open Access
90Y-Labeled Anti-ROBO1 Monoclonal Antibody Exhibits Antitumor Activity against Small Cell Lung Cancer Xenografts
PLoS ONE·2015· 27 citedOpen Access
Relationship between pelvic floor symptoms and POP-Q measurements in pelvic organ prolapse patients in Japan
Physiotherapy·2015
A Low-Dose β1-Blocker in Combination with Milrinone Improves Intracellular Ca2+ Handling in Failing Cardiomyocytes by Inhibition of Milrinone-Induced Diastolic Ca2+ Leakage from the Sarcoplasmic Reticulum
PLoS ONE·2015· 23 citedOpen Access
A 90Y-labelled anti-ROBO1 monoclonal antibody exhibits antitumour activity against hepatocellular carcinoma xenografts during ROBO1-targeted radioimmunotherapy
EJNMMI Research·2014· 25 citedOpen Access
Enhanced binding of calmodulin to RyR2 corrects arrhythmogenic channel disorder in CPVT-associated myocytes
Biochemical and Biophysical Research Communications·2014· 33 cited
Dantrolene inhibits aberrant Ca2+ release by stabilizing inter-domain interactions within the ryanodine receptor in cardiac troponin T-related familial hypertrophic cardiomyopathy
European Heart Journal·2013Open Access
Preclinical evaluation of anti-cadherin 3 human-mouse chimeric monoclonal antibody FF-21101 radioimmunotherapy
2013· 3 cited
Abstract 299: The Cardioprotective Mechanism of a Recombinant Atrial Natriuretic Peptide Against Catecholamine-Induced Myocardial Injury in Acute Heart Failure
Circulation·2012
Abstract 12935: Enhanced Binding of Calmodulin to RyR2 Inhibits Aberrant Ca2+ Release and Arrhythmogenesis in CPVT-Associated Mutation
Circulation·2012
Abstract 9709: CaMKII-mediated Aberrant Ca2+ Release May Play a Key Role in hte Arrhythmogenesis In Cardiac Troponin T-related Familial Hypertrophic Cardiomyopathy
Circulation·2012
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Frequent Co-authors

Masafumi Yano(23), Shigeki Kobayashi(23), Takeshi Yamamoto(22), Shinichi Okuda(21), Takeshi Suetomi(18), Makoto Ono(16), Masahiro Doi(15), Masunori Matsuzaki(15), Masakazu Fukuda(14), Tetsuro Oda(11), Takayoshi Kato(11), Hitoshi Uchinoumi(9), Xiaojuan Xu(8), Hiroki Tateishi(7), Shigehiko Nishimura(7), Takehisa Susa(6), Wakako Murakami(6), Mamoru Mochizuki(6), Noriaki Ikemoto(4), Noritaka Koseki(4)