Harry C. Meeker

New York State Office for People With Developmental Disabilities — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

23h-index2.0kcitations62works0.02yr avg
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Research Topics

Prion Diseases and Protein Misfolding(32), Trace Elements in Health(22), Leprosy Research and Treatment(9), Alzheimer's disease research and treatments(8), Mycobacterium research and diagnosis(7)

Publications62 total

Efficient Delivery of FMR1 across the Blood Brain Barrier Using AAVphp Construct in Adult FMR1 KO Mice Suggests the Feasibility of Gene Therapy for Fragile X Syndrome
Genes·2023· 11 citedOpen Access
Efficient delivery of <i>FMR1</i> across the blood brain barrier using AAVphp construct in adult <i>FMR1</i> KO mice demonstrates the feasibility of gene therapy for fragile X syndrome
2022Open Access
Novel Epigenetic Regulation of Alpha-Synuclein Expression in Down Syndrome
Molecular Neurobiology·2014· 12 cited
Assessment of social interaction and anxiety-like behavior in senescence-accelerated-prone and -resistant mice
Physiology & Behavior·2013· 19 cited
Altered Lymphocyte Proliferation and Innate Immune Function in Scrapie 139A- and ME7-Infected Mice
Viral Immunology·2013· 3 citedOpen Access
Regulation of α‐synuclein expression in down syndrome
Journal of Neuroscience Research·2012· 8 cited
O3‐06‐02: Toll‐like receptor 9 ligand CpG ODN as a new highly effective agent for prevention and/or treatment of Alzheimer's disease
Alzheimer s & Dementia·2009· 1 cited
Upregulation of β-catenin expression in down syndrome model Ts65Dn mouse brain
Neuroscience·2009· 7 cited
Induction of Toll-Like Receptor 9 Signaling as a Method for Ameliorating Alzheimer's Disease-Related Pathology
Journal of Neuroscience·2009· 165 citedOpen Access
Accelerated Prion Disease Pathogenesis in Toll-Like Receptor 4 Signaling-Mutant Mice
Journal of Virology·2008· 52 citedOpen Access
P3‐409: The establishment of astrocyte cell models expressing endogenous MuLV from SAM mice
Alzheimer s & Dementia·2008Open Access
Physiological properties of astroglial cell lines derived from mice with high (SAMP8) and low (SAMR1, ICR) levels of endogenous retrovirus
Retrovirology·2008· 8 citedOpen Access
Pathological Changes in Visual Cortex of Scrapie-Infected Hamsters
2007
CpG oligodeoxynucleotide-enhanced humoral immune response and production of antibodies to prion protein PrPSc in mice immunized with 139A scrapie-associated fibrils
Journal of Leukocyte Biology·2007· 50 cited
Passage of chronic wasting disease prion into transgenic mice expressing Rocky Mountain elk (Cervus elaphus nelsoni) PrPC
Journal of General Virology·2006· 77 cited
Quantitative immunogold study of increased expression of metallothionein-I/II in the brain perivascular areas of diabetic scrapie-infected mice
Journal of Molecular Histology·2006· 4 cited
Scrapie infection activates the replication of ecotropic, xenotropic, and polytropic murine leukemia virus (MuLV) in brains and spinal cords of senescence-accelerated mice: Implication of MuLV in progression of scrapie pathogenesis
Biochemical and Biophysical Research Communications·2006· 22 cited
P4–433: Therapeutically effective anti–prion protein monoclonal antibodies
Alzheimer s & Dementia·2006· 1 citedOpen Access
P4–123: PrP<sup>Sc</sup> Aggregates in the ocular lens of symptomatic and pre–symptomatic prion infected mice
Alzheimer s & Dementia·2006Open Access
Immunogold study of altered expression of some interendothelial junctional molecules in the brain blood microvessels of diabetic scrapie-infected mice
Journal of Molecular Histology·2006· 13 cited
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Frequent Co-authors

Richard I. Carp(24), Thomas Wısnıewskı(13), Richard J. Kascsak(11), William R. Levis(11), Georgia Schuller‐Levis(9), Richard Carp(7), Eugene A. Sersen(7), Daryl S. Spinner(6), Xuemin Ye(6), Regina Kascsak(5), Henrieta Scholtzova(5), Piotr B. Kozlowski(5), A Vorbrodt(5), D. H. Dobrogowska(5), Einar M. Sigurdsson(4), Joanna Pankiewicz(4), Martin Sadowski(4), David R. Brown(3), Blas Frangione(3), Frances Prelli(3)