Leo Price

Crown Bioscience (China) — China

Medicine · Health Sciences

34h-index5.0kcitations128works0.42yr avg
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Research Topics

Cancer Cells and Metastasis(52), 3D Printing in Biomedical Research(45), Cancer Research and Treatments(22), Cell Adhesion Molecules Research(14), Protein Kinase Regulation and GTPase Signaling(10)

Publications128 total

350 Impact of type 2 cytokines on microbiota composition in an ex vivo skin model
Journal of Investigative Dermatology·2025Open Access
Ex vivo 3D micro-tumour testing platform for predicting clinical response to platinum-based therapy in patients with high-grade serous ovarian cancer
npj Precision Oncology·2025· 1 citedOpen Access
Global proteomic profiling of a patient-derived 3D CYST model and reference tissue of polycystic kidney disease
Drug Metabolism and Pharmacokinetics·2025
A Patient‐Derived <scp>3D</scp> Cyst Model of Polycystic Kidney Disease That Mimics Disease Development and Responds to Repurposing Candidates
Clinical and Translational Science·2025· 1 citedOpen Access
84 A high-content screening platform for testing immunotherapies in 100 patient-derived organoid models
Regular and Young Investigator Award Abstracts·2024Open Access
1004 3D<i>ex vivo</i>patient tissue platform feasibility for testing drug responses in primary and metastatic colorectal cancer
Regular and Young Investigator Award Abstracts·2024Open Access
Abstract B040: High-Content Screening to Enhance the Preclinical Development of Immunotherapies, Validated for 100 Patient-Derived Organoids
Cancer Immunology Research·2024
449 (PB437): An IND-ready anti-CD4 monoclonal antibody in combination with PD-1 inhibitors for the treatment of solid tumors
European Journal of Cancer·2024
Abstract LB435: Large panel organoid drug testing combined with biomarker analysis: Unveiling prospects for mechanism of action identification and preclinical patient stratification
Cancer Research·2024· 2 cited
Abstract 87: Integrated pipeline for immuno-oncology drug testing: from patient-derived organoid assays with reconstituted TME to fresh ex vivo patient tissue cultures
Cancer Research·2024
Abstract PR016: Largescale organoid panel drug screening to short-track clinically-relevant output
Molecular Cancer Therapeutics·2023
Abstract LB_B16: Quantification of immune-oncology drug responses in autologous co-cultures of ex vivo patient tumor tissues with PBMCs
Molecular Cancer Therapeutics·2023
77 Analyzing effects of immunotherapies, such as bispecific antibodies and cellular therapy, targeting EGFR expression with a high content screening platform in patient-derived organoids
Regular and Young Investigator Award Abstracts·2023Open Access
963 TME Immune-profiling of<i>ex vivo</i>tumor tissues and their functional responses to immuno-oncology treatments
Regular and Young Investigator Award Abstracts·2023Open Access
Abstract 4570: Expanding the 3D ex vivo patient tissue platform toolbox for (immuno)-oncology drug testing
Cancer Research·2023· 1 cited
Abstract 2822: Maximizing radiotherapy impact: a novel pre-clinical platform for screening of radiosensitizing agents in patient-derived tumor organoids
Cancer Research·2023
Abstract 198: Pan-cancer assay-ready organoid drug screening with robust, reproducible and clinically-relevant output
Cancer Research·2023· 4 cited
Abstract 401: Developing KRAS G12C inhibitor-resistant tumor models for efficacy evaluation of next-generation anticancer therapies
Cancer Research·2023· 1 cited
Abstract 579: Mini-tumors: Pre-clinical HCI assays to screen anti-cancer drugs in the context of organoids, cancer-associated fibroblasts and immune cells
Cancer Research·2023
Abstract 4146: Unlocking IO drug potential by high content imaging of immune cell co-cultures with cancer organoids from diverse cancer indications
Cancer Research·2023
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Frequent Co-authors

Bob van de Water(17), Kuan Yan(9), Johannes L. Bos(8), Tijmen H. Booij(7), Yu Qin(7), Bram Herpers(6), Sreenivasa Ramaiahgari(5), Erik H.J. Danen(5), Anna Koffer(5), Geurt Stokman(5), Jim C. Norman(4), Hester Bange(4), Wouter N. Leonhard(4), Dorien J.M. Peters(4), Frank Schwede(3), John G. Collard(3), John H.N. Meerman(3), Rob C. Roovers(3), Vanessa Zondag-van der Zande(3), John de Kruif(3)