Pablo Pérez‐Piñera

University of Illinois Urbana-Champaign — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

38h-index5.9kcitations113works1.62yr avg
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Research Topics

CRISPR and Genetic Engineering(44), RNA Interference and Gene Delivery(17), Proteoglycans and glycosaminoglycans research(14), RNA and protein synthesis mechanisms(13), Advanced biosensing and bioanalysis techniques(10)

Publications113 total

Abstract A060: Tightly regulated alternative RNA splicing of MAPK3 (ERK1) as a Kras-independent mechanism of oncogenesis in PDAC
Cancer Research·2025
Abstract A100: Systemic targeting of therapeutic RNA into pancreatic tumors via an RNA-binding and cell-penetrating antibody
Cancer Research·2025
Abstract A004: Altered RNA splicing drives pancreatic cancer by mimicking chromosome deletions
Cancer Research·2025
Systemic administration of an RNA binding and cell-penetrating antibody targets therapeutic RNA to multiple mouse models of cancer
Science Translational Medicine·2025· 4 cited
Implementation of an Undergraduate Laboratory-Based Mammalian Genome Editing Course
The CRISPR Journal·2025
SPLICER: a highly efficient base editing toolbox that enables in vivo therapeutic exon skipping
Nature Communications·2024· 4 citedOpen Access
Chromatin-associated lncRNA-splicing factor condensates regulate hypoxia responsive RNA processing of genes pre-positioned near nuclear speckles
2024· 5 citedOpen Access
In vivo CRISPR base editing for treatment of Huntington’s disease
2024· 4 citedOpen Access
SPLICER: A Highly Efficient Base Editing Toolbox That Enables <i>In Vivo</i> Therapeutic Exon Skipping
2024· 2 citedOpen Access
Corrigendum: Chromatin structure and context-dependent sequence features control prime editing efficiency
Frontiers in Genetics·2024Open Access
Editorial overview: The next-generation of genome editing: The future is now
Current Opinion in Biomedical Engineering·2024
Abstract C075: Altered RNA splicing causes pancreatic cancer and exposes a therapeutic vulnerability
Cancer Research·2024
Protein engineering technologies for development of next-generation genome editors
Current Opinion in Biomedical Engineering·2023· 3 citedOpen Access
Targeting Duchenne muscular dystrophy by skipping DMD exon 45 with base editors
Molecular Therapy — Nucleic Acids·2023· 10 citedOpen Access
Chromatin structure and context-dependent sequence features control prime editing efficiency
Frontiers in Genetics·2023· 10 citedOpen Access
Chromatin structure and context-dependent sequence features control prime editing efficiency
2023· 4 citedOpen Access
Delivering Base Editors In Vivo by Adeno-Associated Virus Vectors
Methods in molecular biology·2023· 2 cited
Delineating cooperative effects of Notch and biomechanical signals on patterned liver differentiation
Communications Biology·2022· 10 citedOpen Access
CRISPR base editing of cis-regulatory elements enables the perturbation of neurodegeneration-linked genes
Molecular Therapy·2022· 22 citedOpen Access
CRISPR base editing of <i>cis</i> -regulatory elements enables target gene perturbations
2022Open Access
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Frequent Co-authors

José A. Vega(13), Thomas F. Deuel(13), Charles A. Gersbach(10), Olivia García‐Suárez(10), David G. Ousterout(6), Michael Gapinske(6), Wendy S. Woods(6), Yunchao Chang(6), Juan Cobo(6), Laura Ezquerra(5), Gonzalo Herradón(5), Antonino Germanà(5), M.G. Calavia(5), Timothy K. Lu(4), Jackson Winter(4), Jun S. Song(4), Aurora Astudillo(4), Manuel Menéndez‐González(4), Ami M. Kabadi(3), Pratiksha I. Thakore(3)