Charles A. Gersbach

Duke University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

64h-index22.5kcitations242works6.92yr avg
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Research Topics

CRISPR and Genetic Engineering(136), RNA Interference and Gene Delivery(44), Virus-based gene therapy research(38), Pluripotent Stem Cells Research(34), CAR-T cell therapy research(24)

Publications241 total

The IGVF catalog—from genetic variation to function
Nucleic Acids Research·2025· 3 citedOpen Access
SMARCA2 is an essential and potent cofactor for a specific subset of the glucocorticoid response in A549 cells
2025Open Access
Circuit-specific gene editing for precision modulation of neuronal activity with CRISPR-rabies virus
2025Open Access
A gene regulatory element modulates myosin expression and controls cardiomyocyte response to stress
Genome Research·2025Open Access
Omni-ATAC v1
2025Open Access
RELB Reprograms Exhausted Tumor-Infiltrating Lymphocytes for Improved Adoptive Cell Therapy
2025Open Access
Comprehensive profiling of transcription factors for reprogramming human astrocytes to neuronal cells through endogenous CRISPR-based gene activation
2025Open Access
Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness
Science·2025· 6 cited
A gene regulatory element modulates myosin expression and controls cardiomyocyte response to stress
2025Open Access
Resurrecting a miniature Cas9 ancestor for genome and epigenome editing
Nature Biotechnology·2025
iPSC-derived Hepatocyte TF Perturbseq v1
2025Open Access
Deletion of Exon 51 in a Humanized Duchenne Muscular Dystrophy Mouse Model Abolishes Ventricular Arrhythmia Predisposition
Circulation Genomic and Precision Medicine·2025· 1 cited
Processing samples following intracellular FACS screen v1
2025Open Access
Intracellular MAP2 staining for flow cytometry v1
2025Open Access
Human Primary Astrocyte (hPA) CRISPRa reprogramming protocol v1
2025Open Access
Human Primary Astrocyte (hPA) Culture v1
2025Open Access
Mouse Primary Astrocyte (mPA) isolation and culture v1
2025Open Access
Omni-ATAC v1
2025Open Access
Synthetic biomolecular condensates enhance translation from a target mRNA in living cells
Nature Chemistry·2025· 26 cited
Respiratory pathology in the mdx/utrn-/- mouse: A murine model for Duchenne Muscular Dystrophy (DMD)
PLoS ONE·2025· 7 citedOpen Access
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Frequent Co-authors

Timothy E. Reddy(11), Pratiksha I. Thakore(9), Gregory E. Crawford(9), David G. Ousterout(9), Pablo Pérez‐Piñera(7), Farshid Guilak(7), Isaac B. Hilton(6), Christopher M. Vockley(6), Christopher E. Nelson(6), Lingyun Song(6), Alexias Safi(6), Anthony D’Ippolito(5), D. Dewran Koçak(5), Ami M. Kabadi(5), Lauren R. Polstein(4), Katherine A. Glass(4), Aravind Asokan(4), William H. Majoros(4), Matthew Gemberling(4), Jonathan M. Brunger(4)