Timothy E. Reddy

Duke University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

53h-index25.1kcitations152works7.92yr avg
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Research Topics

Genomics and Chromatin Dynamics(38), CRISPR and Genetic Engineering(29), RNA and protein synthesis mechanisms(21), Epigenetics and DNA Methylation(19), RNA Research and Splicing(12)

Publications146 total

An expanded registry of candidate cis-regulatory elements
Nature·2026· 3 citedOpen Access
The IGVF catalog—from genetic variation to function
Nucleic Acids Research·2025· 3 citedOpen Access
The architecture of allele-specific regulatory variant effects across five human genomes
2025
Cell modeling and rescue of a novel noncoding genetic cause of glycogen storage disease IX
Genetics in Medicine Open·2025Open Access
SMARCA2 is an essential and potent cofactor for a specific subset of the glucocorticoid response in A549 cells
2025Open Access
Comprehensive evaluation of diverse massively parallel reporter assays to functionally characterize human enhancers genome-wide
Genome biology·2025· 3 citedOpen Access
Gene regulatory activity associated with polycystic ovary syndrome revealed DENND1A-dependent testosterone production
Nature Communications·2025· 2 citedOpen Access
The gene regulatory effects of selective glucocorticoid receptor ligands
2025· 1 citedOpen Access
Cell Modeling and Rescue of a Novel Non-coding Genetic Cause of Glycogen Storage Disease IX
2025Open Access
Bayesian estimation of allele-specific expression in the presence of phasing uncertainty
Bioinformatics·2025· 1 citedOpen Access
An Expanded Registry of Candidate cis-Regulatory Elements for Studying Transcriptional Regulation
2024· 9 citedOpen Access
Deciphering the impact of genomic variation on function
Nature·2024· 67 citedOpen Access
Bayesian Estimation of Allele-Specific Expression in the Presence of Phasing Uncertainty
2024Open Access
HyperCas12a enables multiplexed CRISPRi screens
2024· 3 citedOpen Access
Mediator kinase inhibition impedes transcriptional plasticity and prevents resistance to ERK/MAPK-targeted therapy in KRAS-mutant cancers
npj Precision Oncology·2024· 6 citedOpen Access
Gene regulatory activity associated with PCOS revealed <i>DENND1A</i> -dependent testosterone production
2024· 1 citedOpen Access
Epigenome editing of the CFTR-locus for treatment of cystic fibrosis
UNC Libraries·2024Open Access
Multicenter integrated analysis of noncoding CRISPRi screens
Nature Methods·2024· 43 citedOpen Access
TFome CRISPRko screens v1
2023Open Access
TF and epigenetic modifier CRISPRi/a screens in human T cells v1
2023Open Access
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Frequent Co-authors

Gregory E. Crawford(21), Charles A. Gersbach(15), Alexias Safi(13), Lingyun Song(13), Christopher M. Vockley(13), R Myers(11), Alejandro Barrera(11), Florencia Pauli(8), Kevin P. White(8), Jason Gertz(8), William H. Majoros(8), Anthony D’Ippolito(7), Andrew E. Jaffe(7), Mette A. Peters(7), Graham D. Johnson(7), Panos Roussos(7), William L. Lowe(7), Mark Gerstein(6), Pratiksha I. Thakore(6), Harm van Bakel(6)