Lauren R. Polstein

Duke University — United States

Agricultural and Biological Sciences · Life Sciences

7h-index2.4kcitations8works0.02yr avg
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Research Topics

Light effects on plants(6), CRISPR and Genetic Engineering(4), Photoreceptor and optogenetics research(3), RNA and protein synthesis mechanisms(2), Photochromic and Fluorescence Chemistry(2)

Publications8 total

An Engineered Optogenetic Switch for Spatiotemporal Control of Gene Expression, Cell Differentiation, and Tissue Morphogenesis
ACS Synthetic Biology·2017· 40 citedOpen Access
Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2
Nucleic Acids Research·2017· 67 citedOpen Access
Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators
Genome Research·2015· 128 citedOpen Access
A light-inducible CRISPR-Cas9 system for control of endogenous gene activation
Nature Chemical Biology·2015· 639 citedOpen Access
Light-Inducible Gene Regulation with Engineered Zinc Finger Proteins
Methods in molecular biology·2014· 21 citedOpen Access
RNA-guided gene activation by CRISPR-Cas9–based transcription factors
Nature Methods·2013· 1.3k citedOpen Access
Light-Inducible Spatiotemporal Control of Gene Activation by Customizable Zinc Finger Transcription Factors
Journal of the American Chemical Society·2012· 193 citedOpen Access
Photoregulated Gene Expression in Human Cells With Light-Inducible Engineered Transcription Factors
ASME 2012 Summer Bioengineering Conference, Parts A and B·2012

Frequent Co-authors

Charles A. Gersbach(8), Pablo Pérez‐Piñera(2), D. Dewran Koçak(2), Christopher M. Vockley(2), Gregory E. Crawford(2), Timothy E. Reddy(2), Andrew F. Adler(1), Ami M. Kabadi(1), Pratiksha I. Thakore(1), Katherine A. Glass(1), David G. Ousterout(1), Kam W. Leong(1), Farshid Guilak(1), Peggy J. Bledsoe(1), Lingyun Song(1), Alexias Safi(1), Gopal P. Pathak(1), Jessica I. Spiltoir(1), Camilla Höglund(1), Sari Heine-Koskinen(1)