Ramón Guixà-González

SIB Swiss Institute of Bioinformatics — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index1.9kcitations66works12.22yr avg
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Research Topics

Receptor Mechanisms and Signaling(45), Neuropeptides and Animal Physiology(17), Lipid Membrane Structure and Behavior(10), Mass Spectrometry Techniques and Applications(10), Monoclonal and Polyclonal Antibodies Research(10)

Publications66 total

Cyclic peptide inhibitors function as molecular glues to stabilize Gq/11 heterotrimers
Proceedings of the National Academy of Sciences·2025· 2 citedOpen Access
Glue-Tiful Inhibitors: Cyclic Depsipeptides Enhance Protein-Protein Interaction within the Subunits of Heterotrimeric Gq/11 Proteins (Abstract ID: 164994)
Journal of Pharmacology and Experimental Therapeutics·2025Open Access
Large scale investigation of GPCR molecular dynamics data uncovers allosteric sites and lateral gateways
Nature Communications·2025· 38 citedOpen Access
Generic residue numbering of the GAIN domain of adhesion GPCRs
Nature Communications·2025· 6 citedOpen Access
Generic residue numbering of the GAIN domain of adhesion GPCRs
2024Open Access
Mechanistic insights into G-protein coupling with an agonist-bound G-protein-coupled receptor
Nature Structural & Molecular Biology·2024· 27 citedOpen Access
Cyclic peptide inhibitors stabilize Gq/11 heterotrimers
2023· 4 citedOpen Access
Mechanistic insights into G protein association with a G protein-coupled receptor
2023· 1 citedOpen Access
Impact of membrane lipid polyunsaturation on dopamine D2 receptor ligand binding and signalling
HAL (Le Centre pour la Communication Scientifique Directe)·2023· 15 citedOpen Access
Correction: Impact of membrane lipid polyunsaturation on dopamine D2 receptor ligand binding and signaling
Molecular Psychiatry·2023· 1 citedOpen Access
WITHDRAWN: The adhesion GPCR Adgrd1 is a prion protein receptor and a mediator of prion cytotoxicity
2023Open Access
Function and dynamics of the intrinsically disordered carboxyl terminus of β2 adrenergic receptor
Nature Communications·2023· 51 citedOpen Access
Ultrafast structural changes direct the first molecular events of vision
Nature·2023· 116 citedOpen Access
Impact of membrane lipid polyunsaturation on dopamine D2 receptor ligand binding and signaling
Molecular Psychiatry·2023Open Access
ULTRAFAST STRUCTURAL CHANGES DIRECT THE FIRST MOLECULAR EVENTS OF VISION
2022· 6 citedOpen Access
Impact of membrane lipid polyunsaturation on dopamine D2 receptor ligand binding and signaling
2022· 2 citedOpen Access
SCoV2-MD: a database for the dynamics of the SARS-CoV-2 proteome and variant impact predictions
Nucleic Acids Research·2021· 29 citedOpen Access
Chimeric single α-helical domains as rigid fusion protein connections for protein nanotechnology and structural biology
Structure·2021· 10 cited
Unraveling binding mechanism and kinetics of macrocyclic Gαq protein inhibitors
Pharmacological Research·2021· 16 citedOpen Access
Initial structures of macrocyclic Gαq protein inhibitors bound to the Gq heterotrimer
2021Open Access
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Frequent Co-authors

Jana Selent(24), Peter W. Hildebrand(16), Xavier Deupí(13), Johanna K. S. Tiemann(9), Maria Martí-Solano(8), Arnau Cordomí(8), Ismael Rodríguez‐Espigares(7), Manuel Pastor(7), Gebhard F. X. Schertler(7), Guillermo Pérez‐Hernández(7), Juan Manuel Ramírez‐Anguita(6), Toni Giorgino(6), Mariona Torrens‐Fontanals(6), Tomasz Maciej Stępniewski(6), Brian Medel-Lacruz(6), Mireia Olivella(6), Ferrán Sanz(6), Gáspár Pándy‐Szekeres(5), David E. Gloriam(5), Matthew J. Rodrigues(5)