Maria Martí-Solano

University of Cambridge — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index2.4kcitations42works10.52yr avg
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Research Topics

Receptor Mechanisms and Signaling(25), Neuropeptides and Animal Physiology(14), Computational Drug Discovery Methods(7), Protein Kinase Regulation and GTPase Signaling(4), RNA and protein synthesis mechanisms(4)

Publications42 total

Obesity due to MC4R deficiency is associated with reduced cholesterol, triglycerides and cardiovascular disease risk
Nature Medicine·2025· 4 citedOpen Access
Loss-of-function Gα <sub>s</sub> rare disease variants exert mutation-specific effects on GPCR signaling
Science Signaling·2025· 3 citedOpen Access
Large scale investigation of GPCR molecular dynamics data uncovers allosteric sites and lateral gateways
Nature Communications·2025· 38 citedOpen Access
Dual regulation of IP3 receptors by IP3 and PIP2 controls the transition from local to global Ca2+ signals
Molecular Cell·2024· 18 citedOpen Access
Exploring human rare disease variants from a multidimensional perspective illuminates receptor – G protein coupling diversity
2024Open Access
Cancer-Associated Mutations Enhance the Sensitivity of the Trupath Gαq/11 System
SSRN Electronic Journal·2024Open Access
Molecular determinants of ligand efficacy and potency in GPCR signaling
Science·2023· 41 citedOpen Access
A multi-dimensional view of context-dependent G protein-coupled receptor function
Biochemical Society Transactions·2023· 11 citedOpen Access
Cancer-Associated Mutations Enhance The Sensitivity Of The Trupath Gα <sub>Q/11</sub> System
2022· 4 cited
Dissecting the allosteric networks governing agonist efficacy and potency in G protein-coupled receptors
2021· 1 citedOpen Access
Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation
Yearbook of pediatric endocrinology·2021· 1 cited
Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation
Cell Reports·2021· 78 citedOpen Access
Analyzing Kinase Similarity in Small Molecule and Protein Structural Space to Explore the Limits of Multi-Target Screening
Molecules·2021· 16 citedOpen Access
Author Correction: Combinatorial expression of GPCR isoforms affects signalling and drug responses
Nature·2020· 8 citedOpen Access
Combinatorial expression of GPCR isoforms affects signalling and drug responses
Nature·2020· 135 citedOpen Access
Context-Specific Striatal Astrocyte Molecular Responses Are Phenotypically Exploitable
Neuron·2020· 123 citedOpen Access
Publisher Correction: GPCRmd uncovers the dynamics of the 3D-GPCRome
Nature Methods·2020· 3 citedOpen Access
GPCRmd uncovers the dynamics of the 3D-GPCRome
Nature Methods·2020· 187 citedOpen Access
GPCRmd uncovers the dynamics of the 3D-GPCRome
2019· 6 citedOpen Access
A highly conserved δ‐opioid receptor region determines RGS4 interaction
FEBS Journal·2019· 6 citedOpen Access
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Frequent Co-authors

Jana Selent(17), Ferrán Sanz(9), M. Madan Babu(8), Ramón Guixà-González(8), Peter Kolb(7), David E. Gloriam(6), Graham Ladds(6), Tomasz Maciej Stępniewski(5), Brian Medel-Lacruz(5), Peter W. Hildebrand(5), Manuel Pastor(5), Eneko Villanueva(4), Ismael Rodríguez‐Espigares(4), Mariona Torrens‐Fontanals(4), Johanna K. S. Tiemann(4), David Aranda-García(4), Gáspár Pándy‐Szekeres(4), Toni Giorgino(4), Jens Carlsson(4), Sławomir Filipek(4)