Hans‐Gottfried Genieser

Biolog Life Science Institute — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

36h-index5.3kcitations104works0.02yr avg
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Research Topics

Phosphodiesterase function and regulation(28), Receptor Mechanisms and Signaling(16), Chemical Synthesis and Analysis(14), Pancreatic function and diabetes(13), Carbohydrate Chemistry and Synthesis(10)

Publications104 total

Nucleoside analogue activators of cyclic AMP-independent protein kinase A of Trypanosoma
Nature Communications·2019· 53 citedOpen Access
Combination of cGMP analogue and drug delivery system provides functional protection in hereditary retinal degeneration
Proceedings of the National Academy of Sciences·2018· 111 citedOpen Access
New cGMP analogues restrain proliferation and migration of melanoma cells
Oncotarget·2017· 21 citedOpen Access
New dimeric cGMP analogues reduce proliferation in three colon cancer cell lines
European Journal of Medicinal Chemistry·2017· 12 citedOpen Access
The DRUGSFORD project: Preservation of retinal morphology and function in different in vivo models for hereditary retinal degeneration
2016
Melatonin and hydroxytyrosol-rich wines influence the generation of DNA oxidation catabolites linked to mutagenesis after the ingestion of three types of wine by healthy volunteers
Food & Function·2016· 19 cited
DNA catabolites in triathletes: effects of supplementation with an aronia–citrus juice (polyphenols-rich juice)
Food & Function·2016· 15 cited
Application of Synthetic Peptide Arrays To Uncover Cyclic Di-GMP Binding Motifs
Journal of Bacteriology·2015· 16 citedOpen Access
Rp-cAMPS Prodrugs Reveal the cAMP Dependence of First-Phase Glucose-Stimulated Insulin Secretion
Molecular Endocrinology·2015· 38 citedOpen Access
Effect of elite physical exercise by triathletes on seven catabolites of DNA oxidation
Free Radical Research·2015· 33 citedOpen Access
Structure-Guided Design of Selective Epac1 and Epac2 Agonists
PLoS Biology·2015· 80 citedOpen Access
INS-1 Epac1 camps Clone10
2015
ESCA Islet Vm Ca Oscillations
2015
The Chemistry of the Noncanonical Cyclic Dinucleotide 2′3′-cGAMP and Its Analogs
Handbook of experimental pharmacology·2015· 19 cited
GLP1R Signaling Pathways
2015
Medicinal Chemistry of the Noncanonical Cyclic Nucleotides cCMP and cUMP
Handbook of experimental pharmacology·2015· 3 cited
INS1 Clone 10 Epac1 camps
2015
Activation profile of cGMP-dependent protein kinase Iα
BMC Pharmacology and Toxicology·2013Open Access
Stimulation of Proglucagon Gene Expression by Human GPR119 in Enteroendocrine L-cell Line GLUTag
Molecular Endocrinology·2013· 34 citedOpen Access
Analysis of Substrate Specificity and Kinetics of Cyclic Nucleotide Phosphodiesterases with N’-Methylanthraniloyl-Substituted Purine and Pyrimidine 3′,5′-Cyclic Nucleotides by Fluorescence Spectrometry
PLoS ONE·2013· 13 citedOpen Access
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Frequent Co-authors

Frank Schwede(27), Bernd Jastorff(15), Oleg G. Chepurny(9), George G. Holz(9), Elke Butt(8), Colin A. Leech(8), Johannes L. Bos(7), Friedrich W. Herberg(7), Stein Ove Døskeland(6), Igor Dzhura(6), Daniela Bertinetti(6), Wolfgang R. Dostmann(5), Erik Maronde(4), Elvira Dzhura(4), Anne Elisabeth Christensen(3), Holger Rehmann(3), Grant G. Kelley(3), Michael W. Roe(3), Xiangquan Li(3), Johan de Rooij(2)