Patricia L. Earl

Cincinnati Children's Hospital Medical Center — United States

Immunology and Microbiology · Life Sciences

63h-index12.6kcitations165works12.02yr avg
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Research Topics

HIV Research and Treatment(80), Poxvirus research and outbreaks(62), Herpesvirus Infections and Treatments(57), Virus-based gene therapy research(43), Immunotherapy and Immune Responses(30)

Publications165 total

Human monoclonal antibodies targeting A35 protect from death against mpox 2296
The Journal of Immunology·2025Open Access
Human monoclonal antibodies targeting A35 protect from death caused by mpox
Cell·2025· 10 citedOpen Access
Mpox multiprotein virus-like nanoparticle vaccine induces neutralizing and protective antibodies in mice and non-human primates
Nature Communications·2025· 6 citedOpen Access
Antibody Binding and Neutralizing Targets within the Predicted Structure of the Poxvirus Multiprotein Entry-Fusion Complex
2025· 3 citedOpen Access
Amoxicillin Associated Allergic Reactions in Children with Perceived High-Risk Phenotypes are Non-Allergic, Without Any Need for Delay in Challenge
Journal of Allergy and Clinical Immunology·2025Open Access
Serum sickness–like reactions in children taking antibiotics represent a distressing form of infection-associated urticaria and may recur unpredictably in susceptible children
The Journal of Allergy and Clinical Immunology In Practice·2025· 6 citedOpen Access
A functional approach to analyze the genetic basis for differences in virulence of monkeypox virus clades
Emerging Microbes & Infections·2025· 6 citedOpen Access
Mpox mRNA-1769 vaccine inhibits orthopoxvirus replication at intranasal, intrarectal, and cutaneous sites of inoculation
npj Vaccines·2024· 9 citedOpen Access
Mpox mRNA-1769 Vaccine Inhibits Orthopoxvirus Replication at Intranasal, Intrarectal, and Cutaneous Sites of Inoculation
2024· 1 citedOpen Access
Comparison of protection against mpox following mRNA or modified vaccinia Ankara vaccination in nonhuman primates
Cell·2024· 91 citedOpen Access
Same-Day Evaluations for Antibiotic-Associated Reactions: a Single-Center Retrospective Analysis of Penicillin Allergy Testing Services (PATS)
Journal of Allergy and Clinical Immunology·2024Open Access
An mpox virus mRNA-lipid nanoparticle vaccine confers protection against lethal orthopoxviral challenge
Science Translational Medicine·2023· 94 cited
Protection from SARS-CoV-2 Variants by MVAs expressing matched or mismatched S administered intranasally to mice
npj Vaccines·2023· 4 citedOpen Access
Virulence differences of mpox (monkeypox) virus clades I, IIa, and IIb.1 in a small animal model
Proceedings of the National Academy of Sciences·2023· 199 citedOpen Access
A monkeypox mRNA-lipid nanoparticle vaccine targeting virus binding, entry, and transmission drives protection against lethal orthopoxviral challenge
2022· 14 citedOpen Access
Enhanced Protection from SARS-CoV-2 Variants by MVA-Based Vaccines Expressing Matched or Mismatched S Proteins Administered Intranasally to hACE2 Mice
2022Open Access
Virulence Differences of Monkeypox Virus Clades 1, 2a and 2b.1 in a Small Animal Model
2022· 4 cited
Intranasal inoculation of an MVA-based vaccine induces IgA and protects the respiratory tract of hACE2 mice from SARS-CoV-2 infection
Proceedings of the National Academy of Sciences·2022· 61 citedOpen Access
Interferon α/β Decoy Receptor Encoded by a Variant in the Dryvax Smallpox Vaccine Contributes to Virulence and Correlates with Severe Vaccine Side Effects
mBio·2022· 3 citedOpen Access
Outcomes of Penicillin Allergy Testing in Children with High-Risk Reaction Histories
Journal of Allergy and Clinical Immunology·2022
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Frequent Co-authors

Bernard Moss(46), Linda S. Wyatt(14), David C. Montefiori(10), Jeffrey L. Americo(9), Robert W. Doms(5), Rama Rao Amara(5), François Villinger(5), Harriet L. Robinson(5), Igor M. Belyakov(4), Jay A. Berzofsky(4), Christopher C. Broder(4), Silvija I. Staprans(4), John D. Altman(4), Natalia Kozyr(4), Yan Xu(4), James G. Herndon(4), Harold M. McClure(4), Leigh Anne Eller(3), Merlin L. Robb(3), Jeffrey D. Ahlers(3)