Ingrid C. Rulifson

Amgen (United States) — United States

Immunology and Microbiology · Life Sciences

19h-index2.4kcitations35works2.52yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

T-cell and B-cell Immunology(8), Immunotherapy and Immune Responses(8), Pancreatic function and diabetes(7), Endoplasmic Reticulum Stress and Disease(7), Liver Disease Diagnosis and Treatment(6)

Publications35 total

Targeting modulated vascular smooth muscle cells in atherosclerosis via FAP-directed immunotherapy
Science·2026
PNPLA3-I148M is a neomorph that interferes with two primary hepatic triglyceride clearance pathways
Cell Reports·2025Open Access
Use of a Transgenic Human PNPLA3 <sup>I148M</sup> Knock-in Mouse for Translational Safety Evaluations of siRNA Therapeutics
Nucleic Acid Therapeutics·2025Open Access
Targeting RUNX1 in Macrophages Facilitates Cardiac Recovery
2025Open Access
Abstract 2651 PNPLA3-I148M is a Neomorph that Interferes with Two Primary Hepatic Triglyceride Clearance Pathways
Journal of Biological Chemistry·2025Open Access
Targeting Modulated Vascular Smooth Muscle Cells in Atherosclerosis via FAP-Directed Immunotherapy
2025· 1 citedOpen Access
PNPLA3-I148M is a Neomorph that Interferes with Two Primary Hepatic Triglyceride Clearance Pathways
2024· 1 citedOpen Access
RAB18 regulates extrahepatic siRNA-mediated gene silencing efficacy
Molecular Therapy — Nucleic Acids·2024Open Access
The fatty liver disease–causing protein PNPLA3-I148M alters lipid droplet–Golgi dynamics
Proceedings of the National Academy of Sciences·2024· 23 citedOpen Access
RAB18 Regulates Extrahepatic SiRNA-Mediated Gene Silencing Efficacy
2024Open Access
The fatty liver disease-causing protein PNPLA3-I148M alters lipid droplet-Golgi dynamics
2023· 8 citedOpen Access
Multiomics study of nonalcoholic fatty liver disease
Nature Genetics·2022· 212 citedOpen Access
KLF15 cistromes reveal a hepatocyte pathway governing plasma corticosteroid transport and systemic inflammation
Science Advances·2022· 23 citedOpen Access
Identification and Optimization of a Minor Allele-Specific siRNA to Prevent PNPLA3 I148M-Driven Nonalcoholic Fatty Liver Disease
Nucleic Acid Therapeutics·2021· 21 citedOpen Access
In Vitro and in Vivo Analyses Reveal Profound Effects of Fibroblast Growth Factor 16 as a Metabolic Regulator
Journal of Biological Chemistry·2016· 18 citedOpen Access
Identification of Human Islet Amyloid Polypeptide as a BACE2 Substrate
PLoS ONE·2016· 35 citedOpen Access
Trefoil Factor 3 (TFF3) Is Regulated by Food Intake, Improves Glucose Tolerance and Induces Mucinous Metaplasia
PLoS ONE·2015· 37 citedOpen Access
Soluble CLEC2 Extracellular Domain Improves Glucose and Lipid Homeostasis by Regulating Liver Kupffer Cell Polarization
EBioMedicine·2015· 8 citedOpen Access
Inhibition of secreted frizzled-related protein 5 improves glucose metabolism
American Journal of Physiology-Endocrinology and Metabolism·2014· 21 cited
Evaluating insulin secretagogues in a humanized mouse model with functional human islets
Metabolism·2012· 15 cited
page 1 of 2Next →

Frequent Co-authors

Jeffrey A. Bluestone(8), Danielle Pruitt(8), Jiansong Xie(7), John Ferbas(7), Jose Barreda(6), Gregory L. Szot(5), Yang Li(5), Raymond J. Deshaies(5), Jonitha Gardner(4), Ki Jeong Lee(4), Hélène Baribault(4), Oliver Homann(4), David J. Sherman(4), Edward L. LaGory(4), Jason Long(4), Jixin Cui(4), Kenneth A. Newell(3), Zhong Guo(3), Ping Zhou(3), Xiaosu Wu(3)