Chun‐Gang Yang

Chinese Academy of Medical Sciences & Peking Union Medical College — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

3h-index135citations4works0.02yr avg
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Research Topics

Microtubule and mitosis dynamics(4), Cancer Treatment and Pharmacology(4), Cancer therapeutics and mechanisms(2), Cancer-related Molecular Pathways(1), 14-3-3 protein interactions(1)

Publications4 total

Restoration of Microtubule Interaction and Cytotoxicity in D-<i>seco</i> Taxanes upon Incorporation of 20-Hydroxymethyl-4-allyloxy Groups
Organic Letters·2015· 11 cited
Optimization of Taxane Binding to Microtubules: Binding Affinity Dissection and Incremental Construction of a High-Affinity Analog of Paclitaxel
Chemistry & Biology·2008· 77 cited
Overcoming Tumor Drug Resistance with High‐Affinity Taxanes: A SAR Study of C2‐Modified 7‐Acyl‐10‐Deacetyl Cephalomannines
ChemMedChem·2007· 44 cited
Synthesis, biological evaluations, and tubulin binding poses of C-2α sulfur linked taxol analogues
Bioorganic & Medicinal Chemistry Letters·2007· 3 cited

Frequent Co-authors

Wei‐Shuo Fang(4), J. Fernando Dı́az(4), Ruth Matesanz(3), Isabel Barasoaı́n(3), Xuan Li(2), Federico Gago(2), James P. Snyder(2), Lei Wang(1), Concepción de Inés(1), Claire Coderch(1), Jesús Jiménez‐Barbero(1), José M. Andreu(1), Ronghua Liu(1), Frances J. Sharom(1), Dali Yin(1), Shao-Rong Wang(1), Pedro A. Sánchez‐Murcia(1), Ning Yan(1), Gonzalo Sáez-Calvo(1), Lei Wang(1)