J. Fernando Dı́az

Consejo Superior de Investigaciones Científicas — Spain

Biochemistry, Genetics and Molecular Biology · Life Sciences

52h-index9.0kcitations233works2.92yr avg
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Research Topics

Microtubule and mitosis dynamics(99), Cancer Treatment and Pharmacology(78), 14-3-3 protein interactions(44), Synthetic Organic Chemistry Methods(37), Cancer therapeutics and mechanisms(32)

Publications233 total

An atlas of microtubule lattice parameters regulated through ligand binding to the microtubule stabilizing sites
2025· 1 citedOpen Access
Uso de fármacos hipolipemiantes en pacientes con alto y muy alto riesgo cardiovascular en España: un año de seguimiento de la subpoblación española del estudio europeo SANTORINI
Revista Clínica Española·2025· 1 citedOpen Access
Base Isolation System in Essential Facilities: A Literature Review
Lecture notes in civil engineering·2024· 1 cited
Development of Potent Microtubule Targeting Agent by Structural Simplification of Natural Diazonamide
Journal of Medicinal Chemistry·2024· 6 cited
Identification of a Potential Entry-Fusion Complex Based on Sequence Homology of African Swine Fever and Vaccinia Virus
Viruses·2024· 3 citedOpen Access
PM534, an Optimized Target-Protein Interaction Strategy through the Colchicine Site of Tubulin
Journal of Medicinal Chemistry·2024· 7 citedOpen Access
Synthesis and Structure-Activity Relationship Studies of Dioxane- and Oxathiane-Based Analogs of (–)-Zampanolide
2024· 1 citedOpen Access
Tannic Acid and Ethyl Gallate Potentialize Paclitaxel Effect on Microtubule Dynamics in Hep3B Cells
Pharmaceuticals·2023· 4 citedOpen Access
Probing a distinct druggable tubulin binding site with gatorbulins 1–7, their metabolic and physicochemical properties, and pharmacological consequences
Bioorganic & Medicinal Chemistry·2023· 3 citedOpen Access
Modulation of taxane binding to tubulin curved and straight conformations by systematic 3′N modification provides for improved microtubule binding, persistent cytotoxicity and in vivo potency
European Journal of Medicinal Chemistry·2023· 5 citedOpen Access
Cover Feature: Synthesis and Structure‐Activity Relationship Studies of C(13)‐Desmethylene‐(−)‐Zampanolide Analogs (Chem. Eur. J. 36/2023)
Chemistry - A European Journal·2023Open Access
CCDC 1499285: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
CCDC 2191814: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
Synthesis and Structure‐Activity Relationship Studies of C(13)‐Desmethylene‐(−)‐Zampanolide Analogs
Chemistry - A European Journal·2023· 5 citedOpen Access
Abstract 6239: PM534 is a novel microtubule-destabilizing agent with high affinity and potent antineoplastic properties
Cancer Research·2023
Abstract 6243: The novel antitubulin agent PM534 exhibits potent antitumoral and antiangiogenic properties in vitro and in vivo
Cancer Research·2023
Structural insight into the stabilization of microtubules by taxanes
eLife·2023· 57 citedOpen Access
Author response: Structural insight into the stabilization of microtubules by taxanes
2023· 1 citedOpen Access
Maytansinol Functionalization: Towards Useful Probes for Studying Microtubule Dynamics
Chemistry - A European Journal·2023· 4 citedOpen Access
Synthesis and Structure-Activity Relationship Studies of C(13)-Desmethylene-(−)-Zampanolide Analogs
2023· 1 citedOpen Access
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Frequent Co-authors

José M. Andreu(29), Isabel Barasoaı́n(12), A.E. Prota(11), Michel O. Steinmetz(11), Rubén M. Buey(9), Katja Bargsten(8), Ruth Matesanz(7), Karl‐Heinz Altmann(6), John H. Miller(6), Jesús Jiménez‐Barbero(6), Ernest Hamel(5), Peter T. Northcote(5), Ángeles Canales(5), Paraskevi Giannakakou(4), J. Bordas(4), Daniel Lucena‐Agell(4), Javier Rodríguez‐Salarichs(4), Jessica J. Field(3), Pablo Chacón(3), E. Pantos(3)