Ruth Matesanz

National Research Council — LK

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index1.2kcitations33works3.02yr avg
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Research Topics

Microtubule and mitosis dynamics(17), Cancer Treatment and Pharmacology(17), 14-3-3 protein interactions(8), Cancer therapeutics and mechanisms(7), Synthetic Organic Chemistry Methods(4)

Publications33 total

Phospho-regulated tethering of focal adhesion kinase to vinculin links force transduction to focal adhesion signaling
Cell Communication and Signaling·2025· 2 citedOpen Access
Towards an Innate Cell-Environment Nanothermometer
arXiv (Cornell University)·2024Open Access
PM534, an Optimized Target-Protein Interaction Strategy through the Colchicine Site of Tubulin
Journal of Medicinal Chemistry·2024· 7 citedOpen Access
Modulation of taxane binding to tubulin curved and straight conformations by systematic 3′N modification provides for improved microtubule binding, persistent cytotoxicity and in vivo potency
European Journal of Medicinal Chemistry·2023· 5 citedOpen Access
Enzyme adaptation to habitat thermal legacy shapes the thermal plasticity of marine microbiomes
Nature Communications·2023· 24 citedOpen Access
Harnessing <scp>DNA</scp> for nanothermometry
Journal of Biophotonics·2020· 3 citedOpen Access
Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of Tubulin
Cell chemical biology·2017· 80 citedOpen Access
Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones)
Molecules·2016· 8 citedOpen Access
Molecular adaptation of Lactobacillus plantarum WCFS1 to gallic acid revealed by genome-scale transcriptomic signature and physiological analysis
Microbial Cell Factories·2015· 33 citedOpen Access
Identification and Characterization of Carboxyl Esterases of Gill Chamber-Associated Microbiota in the Deep-Sea Shrimp Rimicaris exoculata by Using Functional Metagenomics
Applied and Environmental Microbiology·2015· 38 citedOpen Access
Pressure adaptation is linked to thermal adaptation in salt‐saturated marine habitats
Environmental Microbiology·2014· 47 citedOpen Access
Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances
Bioorganic & Medicinal Chemistry·2014· 34 cited
New Interfacial Microtubule Inhibitors of Marine Origin, PM050489/PM060184, with Potent Antitumor Activity and a Distinct Mechanism
ACS Chemical Biology·2013· 57 cited
A structure-based design of new C2- and C13-substituted taxanes: tubulin binding affinities and extended quantitative structure–activity relationships using comparative binding energy (COMBINE) analysis
Organic & Biomolecular Chemistry·2013· 25 cited
Zampanolide, a Potent New Microtubule-Stabilizing Agent, Covalently Reacts with the Taxane Luminal Site in Tubulin α,β-Heterodimers and Microtubules
Chemistry & Biology·2012· 83 citedOpen Access
Multiple Keys for a Single Lock: The Unusual Structural Plasticity of the Nucleotidyltransferase (4′)/Kanamycin Complex
Chemistry - A European Journal·2012· 12 citedOpen Access
Cyclostreptin Derivatives Specifically Target Cellular Tubulin and Further Map the Paclitaxel Site
Biochemistry·2011· 20 cited
Modulation of Microtubule Interprotofilament Interactions by Modified Taxanes
Biophysical Journal·2011· 34 citedOpen Access
Thermodynamics as a Tool for the Optimization of Drug Binding
InTech eBooks·2011· 2 citedOpen Access
Modulation of microtubule protofilament interactions by modified taxanes
Acta Crystallographica Section A Foundations of Crystallography·2011Open Access
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Frequent Co-authors

J. Fernando Dı́az(22), Isabel Barasoaı́n(13), Jesús Jiménez‐Barbero(10), José M. Andreu(9), Ángeles Canales(9), Wei‐Shuo Fang(9), Benet Pera(8), Javier Rodríguez‐Salarichs(7), Ernest Hamel(4), Enrique Calvo(3), Juan Antonio López(3), Chiara Trigili(3), Chun‐Gang Yang(3), Federico Gago(3), Rafael Bargiela(3), Peter N. Golyshin(3), Manuel Ferrer(3), Aurora Nogales(3), Michael Edler(2), Oriol Pineda(2)