David J. Timson

University of Brighton — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

42h-index6.4kcitations399works0.02yr avg
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Research Topics

Metabolism and Genetic Disorders(52), Enzyme Structure and Function(42), Helminth infection and control(26), Amino Acid Enzymes and Metabolism(25), Parasites and Host Interactions(23)

Publications399 total

Triosephosphate isomerase from <i>Fasciola hepatica</i>: high-resolution crystal structure as a drug target
Acta Crystallographica Section F Structural Biology Communications·2025Open Access
Galactose epimerase deficiency: lessons from the GalNet registry
Orphanet Journal of Rare Diseases·2022· 4 citedOpen Access
L-Asparaginase from Penicillium sizovae Produced by a Recombinant Komagataella phaffii Strain
Pharmaceuticals·2022· 9 citedOpen Access
Targeting HIF-1α Function in Cancer through the Chaperone Action of NQO1: Implications of Genetic Diversity of NQO1
Journal of Personalized Medicine·2022· 18 citedOpen Access
Additional file 1 of Galactose epimerase deficiency: lessons from the GalNet registry
Figshare·2022Open Access
Additional file 2 of Galactose epimerase deficiency: lessons from the GalNet registry
Figshare·2022Open Access
Galactosemia: Towards Pharmacological Chaperones
Journal of Personalized Medicine·2021· 19 citedOpen Access
[<scp><sup>13</sup>C</scp>]‐galactose breath test in a patient with galactokinase deficiency and spastic diparesis
JIMD Reports·2021· 2 citedOpen Access
Yeast Cellular Stress: Impacts on Bioethanol Production
Fermentation·2020· 54 citedOpen Access
The structural and molecular biology of type IV galactosemia
Biochimie·2020· 17 cited
The Catalytic Cycle of the Antioxidant and Cancer-Associated Human NQO1 Enzyme: Hydride Transfer, Conformational Dynamics and Functional Cooperativity
Antioxidants·2020· 33 citedOpen Access
RNA interference dynamics in juvenile Fasciola hepatica are altered during in vitro growth and development
International Journal for Parasitology Drugs and Drug Resistance·2020· 9 citedOpen Access
Galactokinase deficiency: lessons from the GalNet registry
Genetics in Medicine·2020· 25 citedOpen Access
Destressing Yeast for Higher Biofuel Yields: Can Excess Chaotropicity Be Mitigated?
Applied Biochemistry and Biotechnology·2020· 2 citedOpen Access
Pilot Evaluation of Two Fasciola hepatica Biomarkers for Supporting Triclabendazole (TCBZ) Efficacy Diagnostics
Molecules·2020· 2 citedOpen Access
RNA interference dynamics in juvenile <i>Fasciola hepatica</i> are altered during <i>in vitro</i> growth and development
2020· 1 citedOpen Access
The roles and applications of chaotropes and kosmotropes in industrial fermentation processes
World Journal of Microbiology and Biotechnology·2020· 26 citedOpen Access
In silico analysis of the effects of disease-associated mutations of β-hexosaminidase A in Tay‒Sachs disease
Journal of Genetics·2020· 4 citedOpen Access
Targeting HIF-1&amp;alpha; Function in Cancer through the Chaperone Action of NQO1
Preprints.org·2020· 2 citedOpen Access
<i>In Silico</i> Analysis of the Effects of Point Mutations on α-Globin: Implications for α-Thalassemia
Hemoglobin·2020· 1 citedOpen Access
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Frequent Co-authors

Richard J. Reece(12), John E. Hallsworth(9), Hazel M. Holden(6), James B. Thoden(6), Brigitte M. Lobnig(6), Jonathan A. Cray(5), Ángel L. Pey(5), Andrew Stevenson(4), Andrew L. Wong(4), Hugo Ten Cate(4), Hideki Kato(4), Masaomi Nangaku(4), Stefan Kölker(4), Rekha S. Singhal(3), Jan Dijksterhuis(3), Terry J. McGenity(3), Andrew N. W. Bell(3), Dale B. Wigley(3), Alexander K. C. Leung(3), Mary A. Voytek(2)