Leslie Wakefield

Oregon Health & Science University — United States

Medicine · Health Sciences

10h-index1.5kcitations18works0.02yr avg
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Research Topics

Pancreatic function and diabetes(5), Liver physiology and pathology(5), RNA Interference and Gene Delivery(4), Endoplasmic Reticulum Stress and Disease(3), DNA Repair Mechanisms(2)

Publications18 total

Complete correction of murine phenylketonuria by selection-enhanced hepatocyte transplantation
Hepatology·2023· 10 citedOpen Access
In vivo tracing of the Cytokeratin 14 lineages using self-cleaving guide RNAs and CRISPR/Cas9
Developmental Biology·2023Open Access
Complete correction of murine phenylketonuria by selection-enhanced hepatocyte transplantation
2023· 2 citedOpen Access
Strong ubiquitous micro-promoters for recombinant adeno-associated viral vectors
Molecular Therapy — Methods & Clinical Development·2023· 22 citedOpen Access
Fanconi anemia‐isogenic head and neck cancer cell line pairs: A basic and translational science resource
International Journal of Cancer·2023· 8 citedOpen Access
Self-cleaving guide RNAs enable pharmacological selection of precise gene editing events in vivo
Nature Communications·2022· 13 citedOpen Access
Fanconi anemia-isogenic head and neck cancer cell line pairs - a basic and translational science resource
2022Open Access
Development of a Beta Cell-Specific Expression Control Element for Recombinant Adeno-Associated Virus
Human Gene Therapy·2022· 3 citedOpen Access
Proliferative polyploid cells give rise to tumors via ploidy reduction
Nature Communications·2021· 85 citedOpen Access
The Significance of Polyploid Hepatocytes During Aging Process
Cellular and Molecular Gastroenterology and Hepatology·2020· 20 citedOpen Access
In Vivo Lineage Tracing of Polyploid Hepatocytes Reveals Extensive Proliferation during Liver Regeneration
Cell stem cell·2019· 203 citedOpen Access
Endoplasmic Reticulum Stress-Induced Upregulation of STARD1 Promotes Acetaminophen-Induced Acute Liver Failure
Gastroenterology·2019· 135 citedOpen Access
LBP-09-Liver humanization of Fah –/–/Rag2 –/–/Il2rg –/–andnbsp;NOD mice with human hepatocytes homozygous for M148I PNPLA3 allows the assessment of specific genotype contribution to NASH development in vivo.
Journal of Hepatology·2019
Identification and Isolation of Clonogenic Cholangiocyte in Mouse
Methods in molecular biology·2018· 6 cited
Long-Term Correction of Diabetes in Mice by In Vivo Reprogramming of Pancreatic Ducts
Molecular Therapy·2018· 30 citedOpen Access
Bipotential Adult Liver Progenitors Are Derived from Chronically Injured Mature Hepatocytes
Cell stem cell·2014· 523 citedOpen Access
Parallel 21: Molecular and Cellular Biology
Hepatology·2014Open Access
Characterization of a membrane receptor for transforming growth factor-beta in normal rat kidney fibroblasts.
Journal of Biological Chemistry·1984· 472 citedOpen Access

Frequent Co-authors

Markus Grompe(15), Craig Dorrell(4), Amita Tiyaboonchai(4), Anne Vonada(4), Branden Tarlow(3), Carl Pelz(3), Willscott E. Naugler(3), Tomonori Matsumoto(3), Milton J. Finegold(2), Paul T. Spellman(2), Feorillo Galivo(2), Sunghee Chai(2), David Enicks(2), Jeffrey Posey(2), Michael Martinez(2), Cary O. Harding(2), Weiliang Tang(2), Andrew Webster(2), Jeffrey R. Whiteaker(2), Christopher M. Chandler(2)