Hongjin Wen

Medicine · Health Sciences

5h-index1.9kcitations11works0.02yr avg
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Research Topics

Alzheimer's disease research and treatments(3), Advancements in Transdermal Drug Delivery(3), Cutaneous lymphoproliferative disorders research(3), Cholinesterase and Neurodegenerative Diseases(3), Computational Drug Discovery Methods(2)

Publications11 total

Development and validation of a bioanalytical method to quantify povorcitinib in human skin with clinical application
Figshare·2026Open Access
Development and validation of a bioanalytical method to quantify povorcitinib in human skin with clinical application
Figshare·2026Open Access
Development and validation of a bioanalytical method to quantify povorcitinib in human skin with clinical application
Bioanalysis·2025Open Access
Methods for the Simultaneous Uplc-Ms/Ms Analysis of Caffeine and its Four Metabolites in Human Plasma or Simultaneous Uplc-Ms/Ms Analysis of Caffeine-D9 and its Four Metabolites in Human Plasma
SSRN Electronic Journal·2023Open Access
Moderate Reduction of γ-Secretase Attenuates Amyloid Burden and Limits Mechanism-Based Liabilities
Journal of Neuroscience·2007· 79 citedOpen Access
Epidermal Growth Factor Receptor and Notch Pathways Participate in the Tumor Suppressor Function of γ-Secretase
Journal of Biological Chemistry·2007· 92 citedOpen Access
BACE1, a Major Determinant of Selective Vulnerability of the Brain to Amyloid-β Amyloidogenesis, is Essential for Cognitive, Emotional, and Synaptic Functions
Journal of Neuroscience·2005· 518 citedOpen Access
Loss of<i>ALS2</i>Function Is Insufficient to Trigger Motor Neuron Degeneration in Knock-Out Mice But Predisposes Neurons to Oxidative Stress
Journal of Neuroscience·2005· 120 citedOpen Access
O3-05-08 Characterization of γ-secretase complex: analysis of APH-1B deficient mice
Neurobiology of Aging·2004· 1 cited
P1-222 Deletion of BACE1 prevents age-associated neuropathological abnormalities in mutant APP;PS1 mice
Neurobiology of Aging·2004
BACE1 is the major β-secretase for generation of Aβ peptides by neurons
Nature Neuroscience·2001· 1.0k cited

Frequent Co-authors

Donald L. Price(7), Philip C. Wong(7), Huaibin Cai(4), Fiona M. Laird(4), David Borchelt(3), Hsueh‐Cheng Chiang(3), Mohamed H. Farah(2), Guilian Xu(2), Cory Brayton(2), Barbara J. Crain(2), Charles G. Eberhart(2), Guojun Ma(2), Zhiyin Xun(2), Lin Zhang(2), Ryan McGee(2), Phillip Wang(2), Yanshu Wang(1), Diane B. McCarthy(1), Alena Savonenko(1), Kaiwen He(1)