Philip C. Wong

Johns Hopkins University — United States

Medicine · Health Sciences

71h-index22.6kcitations263works9.62yr avg
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Research Topics

Alzheimer's disease research and treatments(85), Amyotrophic Lateral Sclerosis Research(78), Neurogenetic and Muscular Disorders Research(46), Cholinesterase and Neurodegenerative Diseases(29), Prion Diseases and Protein Misfolding(22)

Publications260 total

Characterizing Microstructural and Mechanical Properties of Dancer Achilles Tendon Using Ultrashort Echo Time MRI and Shear Wave Elastography Ultrasound
Journal of Orthopaedic Research®·2025Open Access
Brain Iron as a Surrogate Biomarker of Pathological TDP-43 Identifies Brain Region-Specific Signatures in Ageing, Alzheimer’s Disease and Amyotrophic Lateral Sclerosis
2025Open Access
TDP-43 loss of function drives aberrant splicing in Parkinson’s disease
2025Open Access
Broad brain biodistribution conferred by an AAV to restore TDP-43 function mitigates Frontotemporal Demenia-like deficits
2025Open Access
International Consensus on Palliative Radiotherapy Endpoints for Bone Metastases Trials: Second Update
International Journal of Radiation Oncology*Biology*Physics·2025
CLINICAL DEPLOYMENT AND EVALUATION OF AN AUTOMATED RADIOTHERAPY SCHEDULING SOFTWARE AT A TERTIARY CANCER CENTRE
Radiotherapy and Oncology·2025
Symptomatic treatment by a BBB-permeable AAV engineered to restore TDP-43 function slows motor neuron disease and prevents paralysis
2025Open Access
Serum amyloid P secreted by bone marrow adipocytes drives skeletal amyloidosis
Nature Aging·2025· 3 citedOpen Access
Large-scale RNA-Seq mining reveals ciclopirox olamine induces TDP-43 cryptic exons
Nature Communications·2025· 4 citedOpen Access
A phase I study of the CSF1R inhibitor vimseltinib in combination with the PD-L1 inhibitor avelumab in patients with advanced sarcoma
ESMO Open·2025· 1 citedOpen Access
Inhibition of nonsense-mediated decay in TDP-43 deficient neurons reveals novel cryptic exons
2025· 5 citedOpen Access
Mobile Phone Acquisition of Patient-Reported Outcomes During and After Head and Neck Radiation Therapy
Journal of medical imaging and radiation sciences·2025
Loss of <scp>TDP</scp>‐43 Splicing Repression Occurs in Myonuclei of Inclusion Body Myositis Patients
Annals of Neurology·2025· 4 citedOpen Access
Loss of TDP‐43 function accelerates tauopathy and death of vulnerable neurons by promoting caspase 3‐mediated endoproteolytic cleavage of tau
Alzheimer s & Dementia·2024· 1 citedOpen Access
Novel fluid biomarker detects TDP‐43 loss of function in individuals at elevated risk of Alzheimer’s disease
Alzheimer s & Dementia·2024· 1 citedOpen Access
Developing Cryptic ACTL6B as Novel TDP‐43 Loss of Function Biomarker
Alzheimer s & Dementia·2024Open Access
Validation of an AAV gene therapy designed to complement the loss of TDP‐43 splicing repression for ALS‐FTD
Alzheimer s & Dementia·2024Open Access
Depletion of TDP-43 exacerbates tauopathy-dependent brain atrophy by sensitizing vulnerable neurons to caspase 3-mediated endoproteolysis of tau in a mouse model of Multiple Etiology Dementia
2024· 3 citedOpen Access
Elevated nuclear TDP-43 induces constitutive exon skipping
Molecular Neurodegeneration·2024· 20 citedOpen Access
FRI-256-YI Patients with metabolic-associated steatotic liver disease and portal hypertension have different skeletal muscle and adipose tissue mass than patients with other causes of cirrhosis
Journal of Hepatology·2024
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Frequent Co-authors

Donald L. Price(23), Don W. Cleveland(11), David Borchelt(9), Sangram S. Sisodia(8), Huaibin Cai(7), Jonathan P. Ling(6), Fiona M. Laird(6), Riqiang Yan(5), Michael K. Lee(4), Juan C. Troncoso(4), Mohamed H. Farah(4), Gopal Thinakaran(4), Jeffrey D. Rothstein(4), Hongjin Wen(3), Robert Vassar(3), Jamuna R. Subramaniam(3), Kulandaivelu S. Vetrivel(3), Po‐Min Chiang(3), Yun Ha Jeong(3), Ahmet Höke(3)