Don W. Cleveland

University of California San Diego — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

165h-index101.2kcitations525works7.52yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Microtubule and mitosis dynamics(178), Amyotrophic Lateral Sclerosis Research(171), Neurogenetic and Muscular Disorders Research(115), Genomics and Chromatin Dynamics(73), Chromosomal and Genetic Variations(57)

Publications525 total

Statins and genetic inhibition of the mevalonate pathway activate an ATF3-STMN2 regenerative program
2026Open Access
Multimodal spatial transcriptomics determines repeat expansion, huntingtin aggregation, and selective cortical neuron loss in Huntington’s Disease
2025Open Access
Chromothripsis and ecDNA initiated by N4BP2 nuclease fragmentation of cytoplasm-exposed chromosomes
Science·2025· 2 citedOpen Access
Dual-targeting snRNA gene therapy rescues STMN2 and UNC13A splicing in TDP-43 proteinopathies
2025Open Access
TDP-43 skein-like inclusions are formed by BAG3- and HSP70-guided co-aggregation with actin-binding proteins
Nature Cell Biology·2025· 2 citedOpen Access
Author Correction: A two-step mechanism for epigenetic specification of centromere identity and function
Nature Cell Biology·2025Open Access
Stathmin-2 enhances motor axon regeneration after injury independent of its binding to tubulin
Proceedings of the National Academy of Sciences·2025· 11 citedOpen Access
Abstract 2192 Evaluating the roles of Rho family GTPases in basophilic KU812 cell degranulation
Journal of Biological Chemistry·2025Open Access
Unraveling the Mysteries of Autism through Biochemically Characterizing the Role of LINC00896 RNA in Cortex Neuronal Cells
2025
Progesterone Promotes Anti-Anxiety/Depressant-like Behavior and Trophic Actions of BDNF in the Hippocampus of Female Nuclear Progesterone Receptor, but Not 5α-Reductase, Knockout Mice
International Journal of Molecular Sciences·2025· 4 citedOpen Access
Aberrant splicing in Huntington’s disease accompanies disrupted TDP-43 activity and altered m6A RNA modification
Nature Neuroscience·2025· 27 citedOpen Access
CK1δ/ε-mediated TDP-43 phosphorylation contributes to early motor neuron disease toxicity in amyotrophic lateral sclerosis
Acta Neuropathologica Communications·2024· 5 citedOpen Access
CK1δ/e-mediated TDP-43 phosphorylation contributes to early motor neuron disease toxicity in amyotrophic lateral sclerosis
2024· 1 citedOpen Access
Acetylation of lysine 82 initiates TDP-43 nuclear loss of function by disrupting its nuclear import
2024· 3 cited
Frontotemporal dementia-like disease progression elicited by seeded aggregation and spread of FUS
Molecular Neurodegeneration·2024· 10 citedOpen Access
Frontotemporal dementia-like disease progression elicited by seeded aggregation and spread of FUS
2024Open Access
CK1δ/ε kinases regulate TDP-43 phosphorylation and are therapeutic targets for ALS-related TDP-43 hyperphosphorylation
Neurobiology of Disease·2024· 13 citedOpen Access
A phage nucleus-associated RNA-binding protein is required for jumbo phage infection
Nucleic Acids Research·2024· 20 citedOpen Access
Re-activation of neurogenic niches in aging brain
2024· 3 citedOpen Access
Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimer’s disease
Acta Neuropathologica·2024· 54 citedOpen Access
page 1 of 27Next →

Frequent Co-authors

Clotilde Lagier‐Tourenne(8), Magdalini Polymenidou(7), Shuo‐Chien Ling(6), C. Frank Bennett(6), Séverine Boillée(5), Marc W. Kirschner(4), Michael K. Lee(4), Donald L. Price(4), Jeffrey D. Rothstein(4), G Yeo(4), Beth A.A. Weaver(4), Michael W. Baughn(4), John Ravits(4), Sandrine Da Cruz(4), Neal G. Copeland(3), Philip C. Wong(3), David Borchelt(3), Sangram S. Sisodia(3), Lucie Bruijn(3), Kasey R. Hutt(3)