Simon H. Stam

Biochemistry, Genetics and Molecular Biology · Life Sciences

5h-index146citations6works0.02yr avg
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Research Topics

Enzyme Catalysis and Immobilization(3), Chemical Synthesis and Analysis(2), Plant biochemistry and biosynthesis(2), Steroid Chemistry and Biochemistry(2), Computational Drug Discovery Methods(1)

Publications6 total

Substrate-based inhibitors of lanosterol 14.alpha.-methyl demethylase: I. Assessment of inhibitor structure-activity relationship and cholesterol biosynthesis inhibition properties
Biochemistry·1995· 31 cited
Substrate-based inhibitors of lanosterol 14.alpha.-methyl demethylase: II. Time-dependent enzyme inactivation by selected oxylanosterol analogs
Biochemistry·1995· 15 cited
Mechanistic studies of lanosterol 14 alpha-methyl demethylase: substrate requirements for the component reactions catalyzed by a single cytochrome P-450 isozyme.
Journal of Lipid Research·1989· 52 citedOpen Access
ChemInform Abstract: Synthesis of 2′(S),3′(R),5′‐Trihydroxypentyladenine (I).
ChemInform·1988
Synthesis of 2′(S), 3′(R),5′-trihydroxypentyladenine
Tetrahedron Letters·1988· 6 cited
In situ accumulation of 3 beta-hydroxylanost-8-en-32-aldehyde in hepatocyte cultures. A putative regulator of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity.
Journal of Biological Chemistry·1987· 42 citedOpen Access

Frequent Co-authors

Robert T. Fischer(4), Paul Johnson(3), Soo S. Ko(3), Ronald L. Magolda(3), J.L. Gaylor(3), J M Trzaskos(2), Margaret Favata(2), James M. Trzăskos(2), Joseph M. Salvino(2), Chia‐Lin J. Wang(1), Chien‐Jen Wang(1)