J M Trzaskos

Biochemistry, Genetics and Molecular Biology · Life Sciences

21h-index2.8kcitations41works0.02yr avg
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Research Topics

Steroid Chemistry and Biochemistry(10), Pharmacogenetics and Drug Metabolism(9), Cholesterol and Lipid Metabolism(9), Inflammatory mediators and NSAID effects(6), Pleural and Pulmonary Diseases(3)

Publications41 total

CCDC 670062: Experimental Crystal Structure Determination
The Cambridge Structural Database·2008Open Access
The map kinase ERK regulates renal activity of cyclin-dependent kinase 2 in experimental glomerulonephritis
Nephrology Dialysis Transplantation·2007· 14 citedOpen Access
Recent Advances in Inflammatory and Immunological Diseases: Focus on Arthritis Therapy
Elsevier eBooks·2007· 1 cited
Regulation of cocaine-induced activator protein 1 transcription factors by the extracellular signal-regulated kinase pathway
Neuroscience·2005· 27 cited
Aggrecanase: The Family and Its Inhibitors
Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents·2005· 20 cited
Regulation of ERK by cannabinoids in hippocampes.
SPIRE - Sciences Po Institutional REpository·2003· 1 cited
Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdelta
Genes & Development·1999· 591 citedOpen Access
Purification and Cloning of Aggrecanase-1: A Member of the ADAMTS Family of Proteins
Science·1999· 686 cited
A high throughput enzymatic assay for stromelysin-1
Inflammation Research·1997
ChemInform Abstract: Chemistry and Pharmacokinetics of Diarylthiophenes and Terphenyls as Selective COX‐2 Inhibitors.
ChemInform·1997
Hepatic cholesterol metabolism in patients with cholesterol gallstones: Enhanced intracellular transport of cholesterol
Gastroenterology·1996· 49 citedOpen Access
ChemInform Abstract: Antiinflammatory 4,5‐Diarylpyrroles. Part 2. Activity as a Function of Cyclooxygenase‐2 Inhibition.
ChemInform·1996· 2 cited
Antiinflammatory 4,5-Diarylpyrroles. 2. Activity as a Function of Cyclooxygenase-2 Inhibition
Journal of Medicinal Chemistry·1995· 120 citedOpen Access
Mechanism of selective inhibition of the inducible isoform of prostaglandin G/H synthase.
Proceedings of the National Academy of Sciences·1994· 410 citedOpen Access
Post-transcriptional Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme-A Reductase by 3β-Hydroxy-Lanost-8-en-32-Al, an Intermediate in the Conversion of Lanosterol to Cholesterol
Archives of Biochemistry and Biophysics·1994· 29 cited
Modulation of 3-hydroxy-3-methylglutaryl-CoA reductase by 15 alpha-fluorolanost-7-en-3 beta-ol. A mechanism-based inhibitor of cholesterol biosynthesis.
Journal of Biological Chemistry·1993· 49 citedOpen Access
Angiotensin II Receptors in Rabbit Vascular Grafts
Biochemical and Biophysical Research Communications·1993· 7 cited
Lanosterol 14 alpha-methyl demethylase. Isolation and characterization of the third metabolically generated oxidative demethylation intermediate.
Journal of Biological Chemistry·1991· 119 citedOpen Access
Mechanistic studies of lanosterol 14 alpha-methyl demethylase: substrate requirements for the component reactions catalyzed by a single cytochrome P-450 isozyme.
Journal of Lipid Research·1989· 52 citedOpen Access
Comparative effects of the azole-based fungicide flusilazole on yeast and mammalian lanosterol 14 alpha-methyl demethylase
Antimicrobial Agents and Chemotherapy·1989· 22 cited
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Frequent Co-authors

Robert T. Fischer(8), J.L. Gaylor(8), Margaret Favata(6), Robert A. Copeland(4), Ronald L. Magolda(4), Satoshi Kawata(4), G Szumiłowicz(4), D Stankiewicz-Borkiel(4), Robert Newton(3), M Covington(3), Soo S. Ko(3), Ali Shafiee(3), Deborah A. Leonard(3), S Wiechowski(3), Michael A. Pratta(2), Elizabeth C. Arner(2), Donald Pinto(2), W. W. WILKERSON(2), Simon H. Stam(2), Paul Johnson(2)