Pavan Krishnamurthy

Oligomerix (United States) — United States

Medicine · Health Sciences

14h-index2.0kcitations30works0.02yr avg
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Research Topics

Alzheimer's disease research and treatments(25), Neuroscience and Neuropharmacology Research(11), Cholinesterase and Neurodegenerative Diseases(7), Neuroinflammation and Neurodegeneration Mechanisms(6), Computational Drug Discovery Methods(5)

Publications30 total

<i>In Vivo</i> Validation of a Small Molecule Inhibitor of Tau Self-Association in htau Mice
Journal of Alzheimer s Disease·2019· 15 citedOpen Access
A novel technology for objective, accurate and non-invasive early diagnosis and monitoring of Alzheimer’s disease in clinics and clinical trials
2019Open Access
[P4–589]: CNS DRUG‐LIKE INHIBITORS OF TAU OLIGOMERIZATION
Alzheimer s & Dementia·2017· 1 cited
P1‐084: Small Molecule TAU Oligomerization Inhibitors
Alzheimer s & Dementia·2016· 3 cited
Sex and Immunogen-Specific Benefits of Immunotherapy Targeting Islet Amyloid Polypeptide in Transgenic and Wild-Type Mice
Frontiers in Endocrinology·2016· 1 citedOpen Access
P4‐319: Characterization of tool compounds targeting tau oligomers
Alzheimer s & Dementia·2015
Antibody-Derived<i>In Vivo</i>Imaging of Tau Pathology
Journal of Neuroscience·2014· 68 citedOpen Access
IC‐P‐214: TAU ANTIBODY DERIVATIVES AS DIAGNOSTIC IMAGING AGENTS FOR TAUOPATHIES
Alzheimer s & Dementia·2014Open Access
P4‐212: DRUG DEVELOPMENT OF INHIBITORS OF TAU OLIGOMER FORMATION FOR ALZHEIMER'S DISEASE AND TAUOPATHIES
Alzheimer s & Dementia·2014· 1 cited
O4‐02‐02: TAU ANTIBODY DERIVATIVES AS DIAGNOSTIC IMAGING AGENTS FOR TAUOPATHIES
Alzheimer s & Dementia·2014
Tau pathology induces loss of GABAergic interneurons leading to altered synaptic plasticity and behavioral impairments
Acta Neuropathologica Communications·2013· 134 citedOpen Access
Non-invasive, in vivo monitoring of neuronal transport impairment in a mouse model of tauopathy using MEMRI
NeuroImage·2012· 31 citedOpen Access
O1‐02‐05: Loss of GABAergic interneuron in a mouse model for tau pathology resulting in altered synaptic plasticity and behavior
Alzheimer s & Dementia·2012Open Access
P2‐530: Immunization with a pseudo‐phosphorylated tau epitope clears tau pathology in a mouse model
Alzheimer s & Dementia·2011· 1 cited
Therapeutic applications of antibodies in non-infectious neurodegenerative diseases
New Biotechnology·2011· 7 citedOpen Access
Mechanistic Studies of Antibody-Mediated Clearance of Tau Aggregates Using an ex vivo Brain Slice Model
Frontiers in Psychiatry·2011· 73 citedOpen Access
P1‐355: Mechanistic studies of antibody mediated clearance of tau aggregates using an ex vivo brain slice model
Alzheimer s & Dementia·2010· 2 cited
O2‐04‐01: Tract‐tracing MEMRI study on a mouse model of tauopathy: Does manganese propagation reflect only axonal transport?
Alzheimer s & Dementia·2010
O2‐05‐01: Immunotherapy targeting Alzheimer's phospho‐tau epitope within the microtubule binding region of tau clears pathological tau and prevents functional decline in a mouse model of tauopathy
Alzheimer s & Dementia·2009· 6 citedOpen Access
Anesthesia-Induced Hyperphosphorylation Detaches 3-Repeat Tau from Microtubules without Affecting Their Stability<i>In Vivo</i>
Journal of Neuroscience·2008· 78 citedOpen Access
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Frequent Co-authors

Einar M. Sigurdsson(13), Hameetha B. Rajamohamedsait(8), Emmanuel Planel(6), Karen Duff(6), Eliot J. Davidowitz(5), James G. Moe(5), Lili Wang(4), Wen Yi(4), Mathieu Herman(4), Gail V.W. Johnson(4), Wajitha J. Rajamohamedsait(4), Wai Haung Yu(3), Helen Y. Figueroa(3), Giulia Papiani(3), Li Liu(2), Josien Levenga(2), Helen Wong(2), Charles A. Hoeffer(2), Alexis Bretteville(2), Yan Deng(2)