Tesa Severson

The Netherlands Cancer Institute — Netherlands

Biochemistry, Genetics and Molecular Biology · Life Sciences

30h-index7.1kcitations138works4.02yr avg
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Research Topics

Estrogen and related hormone effects(40), RNA Research and Splicing(26), MicroRNA in disease regulation(21), Prostate Cancer Treatment and Research(20), Cancer Genomics and Diagnostics(16)

Publications138 total

Fasting boosts breast cancer therapy efficacy via glucocorticoid activation
Nature·2025· 1 citedOpen Access
TRIM24 as a therapeutic target in endocrine treatment–resistant breast cancer
Proceedings of the National Academy of Sciences·2025· 3 citedOpen Access
Epigenetic profiling identifies markers of endocrine resistance and therapeutic options for metastatic castration-resistant prostate cancer
Cell Reports Medicine·2025· 4 citedOpen Access
Endometrial tumorigenesis involves epigenetic plasticity demarcating non-coding somatic mutations and 3D-genome alterations
Genome biology·2025· 3 citedOpen Access
Genomic and transcriptomic features of androgen receptor signaling inhibitor resistance in metastatic castration-resistant prostate cancer
Journal of Clinical Investigation·2024· 9 citedOpen Access
Enhancer plasticity in endometrial tumorigenesis demarcates non-coding somatic mutations and 3D-genome alterations boosting the oncogenic driver ESR1
2023Open Access
Grade Group 1 Prostate Cancers Exhibit Tumor-defining Androgen Receptor–driven Programs
European Urology·2023· 10 citedOpen Access
Abstract A029: Whole genome and transcriptome analysis of paired metastatic biopsies identified resistance mechanisms in castration-resistant prostate cancer
Cancer Research·2023
PAXIP1 and STAG2 converge to maintain 3D genome architecture and facilitate promoter/enhancer contacts to enable stress hormone-dependent transcription
Nucleic Acids Research·2023· 20 citedOpen Access
Data from Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence
2023Open Access
Supplementary Figure from Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence
2023Open Access
Supplementary Figure from Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence
2023Open Access
Data from Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence
2023Open Access
Supplementary Data from Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence
2023Open Access
Supplementary Data from Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence
2023Open Access
Figure S1 from EZH2 Is Overexpressed in <i>BRCA1</i>-like Breast Tumors and Predictive for Sensitivity to High-Dose Platinum-Based Chemotherapy
2023Open Access
Supplementary Legend from EZH2 Is Overexpressed in <i>BRCA1</i>-like Breast Tumors and Predictive for Sensitivity to High-Dose Platinum-Based Chemotherapy
2023Open Access
Data from EZH2 Is Overexpressed in <i>BRCA1</i>-like Breast Tumors and Predictive for Sensitivity to High-Dose Platinum-Based Chemotherapy
2023Open Access
Data from EZH2 Is Overexpressed in <i>BRCA1</i>-like Breast Tumors and Predictive for Sensitivity to High-Dose Platinum-Based Chemotherapy
2023Open Access
Figure S2 from EZH2 Is Overexpressed in <i>BRCA1</i>-like Breast Tumors and Predictive for Sensitivity to High-Dose Platinum-Based Chemotherapy
2023Open Access
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Frequent Co-authors

Wilbert Zwart(22), Lodewyk F.A. Wessels(15), Sabine C. Linn(13), Andries M. Bergman(11), Ryan D. Morin(9), Marco A. Marra(9), Yanyun Zhu(8), Yongjun Zhao(7), Richard A. Moore(7), Steven J.M. Jones(7), Matthew L. Freedman(7), Karianne Schuurman(7), Martin Hirst(6), Carlos Caldas(6), Jelle Wesseling(6), René Bernards(6), Mark Opdam(6), Jianghong An(5), Sohrab P. Shah(5), Robert A. Holt(5)