Gertrude B. Elion

Boston University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

63h-index17.3kcitations222works0.02yr avg
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Research Topics

Biochemical and Molecular Research(50), Herpesvirus Infections and Treatments(32), Cytomegalovirus and herpesvirus research(26), HIV/AIDS drug development and treatment(23), Adenosine and Purinergic Signaling(17)

Publications222 total

Phase I Study of 506U78 Administered on a Consecutive 5-Day Schedule in Children and Adults With Refractory Hematologic Malignancies
Journal of Clinical Oncology·2005· 174 citedOpen Access
Schedule-dependent activity of temozolomide plus CPT-11 against a human central nervous system tumor-derived xenograft.
PubMed·2000· 70 cited
Schedule-dependent activity of irinotecan plus BCNU against malignant glioma xenografts
Cancer Chemotherapy and Pharmacology·2000· 35 cited
The selectivity of action of an antiherpetic agent, 9‐(2‐hydroxyethoxymethyl) guanine
Reviews in Medical Virology·1999· 80 cited
The selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanine
Reviews in Medical Virology·1999· 64 cited
Personal Reflections
Annals of the New York Academy of Sciences·1999
Therapeutic efficacy of vinorelbine against pediatric and adult central nervous system tumors
Cancer Chemotherapy and Pharmacology·1998· 18 cited
Enhancement of irinotecan (CPT-11) activity against central nervous system tumor xenografts by alkylating agents
Cancer Chemotherapy and Pharmacology·1998· 62 cited
Characterization of the mechanisms of busulfan resistance in a human glioblastoma multiforme xenograft
Cancer Chemotherapy and Pharmacology·1997· 7 cited
Thiopurine biology and pharmacology
Trends in Pharmacological Sciences·1997· 129 cited
L -Amino acid oxidase (LOX) modulation of melphalan activity against intracranial glioma
Cancer Chemotherapy and Pharmacology·1996· 7 cited
Therapeutic efficacy of the topoisomerase I inhibitor 7-ethyl-10-(4-[1-piperidino]-1-piperidino)-carbonyloxy-camptothecin against pediatric and adult central nervous system tumor xenografts
Cancer Chemotherapy and Pharmacology·1996· 104 cited
Enhancement of melphalan activity by inhibition of DNA polymerase-α and DNA polymerase-β
Cancer Chemotherapy and Pharmacology·1996· 6 cited
The effect of L-amino acid oxidase on activity of melphalan against an intracranial xenograft
Cancer Chemotherapy and Pharmacology·1995
Flunarizine enhancement of melphalan activity against drug-sensitive/resistant rhabdomyosarcoma
British Journal of Cancer·1995· 11 cited
The effect ofl-amino acid oxidase on activity of melphalan against an intracranial xenograft
Cancer Chemotherapy and Pharmacology·1995· 3 cited
Busulfan therapy of central nervous system xenografts in athymic mice
Cancer Chemotherapy and Pharmacology·1994
Busulfan therapy of central nervous system xenografts in athymic mice
Cancer Chemotherapy and Pharmacology·1994· 23 cited
The Pharmacology of Azathioprine
Annals of the New York Academy of Sciences·1993· 154 cited
The Quest for a Cure
The Annual Review of Pharmacology and Toxicology·1993· 24 cited
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Frequent Co-authors

George H. Hitchings(17), Thomas A. Krenitsky(7), James A. Fyfe(5), P de Miranda(5), P A Furman(5), Henry Vanderwerff(5), Paul M. Keller(4), M H St Clair(4), Elvira A. Falco(4), Phillip A. Furman(3), Lilia M. Beauchamp(3), Richard L. Miller(3), Janet L. Rideout(3), Peter B. Russell(3), L M Beacham(3), Carol M. Lubbers(3), Howard J. Schaeffer(2), Vincent Massey(2), Graham Palmer(2), R. Wayne Rundles(2)