Amit A. Upadhyay

Emory University — United States

Immunology and Microbiology · Life Sciences

22h-index3.8kcitations54works3.82yr avg
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Research Topics

T-cell and B-cell Immunology(11), COVID-19 Clinical Research Studies(11), Immune Cell Function and Interaction(11), HIV Research and Treatment(10), SARS-CoV-2 and COVID-19 Research(10)

Publications54 total

Primate resident memory T cells activate humoral and stromal immunity
Immunity·2025· 2 cited
Diverse priming outcomes under conditions of very rare precursor B cells
Immunity·2025· 8 citedOpen Access
Passive infusion of an S2-Stem broadly neutralizing antibody protects against SARS-CoV-2 infection and lower airway inflammation in rhesus macaques
PLoS Pathogens·2025· 1 citedOpen Access
A Broad Survey and Functional Analysis of Immunoglobulin Loci Variation in Rhesus Macaques
2025· 10 citedOpen Access
Diverse priming outcomes under conditions of very rare precursor B cells
2024· 1 citedOpen Access
Passive infusion of an S2-Stem broadly neutralizing antibody protects against SARS-CoV-2 infection and lower airway inflammation in rhesus macaques
2024Open Access
Natural killer-like B cells are a distinct but infrequent innate immune cell subset modulated by SIV infection of rhesus macaques
PLoS Pathogens·2024· 6 citedOpen Access
Frequency-potency analysis of IgG+ memory B cells delineates neutralizing antibody responses at single-cell resolution
Cell Reports·2024· 2 citedOpen Access
High throughput analysis of B cell dynamics and neutralizing antibody development during immunization with a novel clade C HIV-1 envelope
PLoS Pathogens·2023· 3 citedOpen Access
Intradermal but not intramuscular modified vaccinia Ankara immunizations protect against intravaginal tier2 simian-human immunodeficiency virus challenges in female macaques
Nature Communications·2023· 16 citedOpen Access
Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques
Science Immunology·2023· 27 citedOpen Access
TREM2+ and interstitial-like macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques
Nature Communications·2023· 35 citedOpen Access
Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques
2022· 9 citedOpen Access
A neutralizing antibody target in early HIV-1 infection was recapitulated in rhesus macaques immunized with the transmitted/founder envelope sequence
PLoS Pathogens·2022· 4 citedOpen Access
Infiltration of inflammatory macrophages and neutrophils and widespread pyroptosis in lung drive influenza lethality in nonhuman primates
PLoS Pathogens·2022· 52 citedOpen Access
From structure to sequence: Antibody discovery using cryoEM
Science Advances·2022· 45 citedOpen Access
TREM2+ and interstitial macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques
2021· 8 citedOpen Access
Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection
PLoS Pathogens·2021· 17 citedOpen Access
IL-21 and IFNα therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques
Nature Communications·2021· 39 citedOpen Access
From Structure to Sequence: Identification of polyclonal antibody families using cryoEM
2021· 1 citedOpen Access
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Frequent Co-authors

Steven E. Bosinger(42), Guido Silvestri(16), Shane Crotty(15), Gregory K. Tharp(14), Kathryn L. Pellegrini(13), Diane G. Carnathan(10), Samantha Reiss(10), Amber Wolabaugh(10), Nirav Patel(10), William R. Schief(10), Mirko Paiardini(10), Thomas H. Vanderford(9), Justin Harper(8), Colin Havenar‐Daughton(8), Bali Pulendran(7), Chiamaka A. Enemuo(7), Dennis R. Burton(7), Darrell J. Irvine(7), Arun K. Boddapati(7), Elise G. Viox(7)