Yu Sakurai

Tohoku University — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

41h-index9.4kcitations157works9.32yr avg
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Research Topics

RNA Interference and Gene Delivery(48), Nanoparticle-Based Drug Delivery(36), Advanced biosensing and bioanalysis techniques(19), Nanoplatforms for cancer theranostics(14), Immunotherapy and Immune Responses(13)

Publications157 total

The stress-responsive cytotoxic effect of diesel exhaust particles on lymphatic endothelial cells
Scientific Reports·2024· 8 citedOpen Access
Lymphatic Endothelial Cells Produce Chemokines in Response to the Lipid Nanoparticles Used in RNA Vaccines
Biological and Pharmaceutical Bulletin·2024· 5 citedOpen Access
The Effect of Cholesterol Content on the Adjuvant Activity of Nucleic-Acid-Free Lipid Nanoparticles
Pharmaceutics·2024· 15 citedOpen Access
Development of a Ready-to-Use-Type RNA Vaccine Carrier Based on an Intracellular Environment-Responsive Lipid-like Material with Immune-Activating Vitamin E Scaffolds
Pharmaceutics·2023· 6 citedOpen Access
An Ionizable Lipid Material with a Vitamin E Scaffold as an mRNA Vaccine Platform for Efficient Cytotoxic T Cell Responses
ACS Nano·2023· 40 citedOpen Access
Tolerogenic Lipid Nanoparticles for Delivering Self-Antigen mRNA for the Treatment of Experimental Autoimmune Encephalomyelitis
Pharmaceuticals·2023· 20 citedOpen Access
Logistics and distribution of small extracellular vesicles from the subcutaneous space to the lymphatic system
Journal of Controlled Release·2023· 10 cited
Development of an Alcohol Dilution–Lyophilization Method for the Preparation of mRNA-LNPs with Improved Storage Stability
Pharmaceutics·2023· 18 citedOpen Access
Ready-to-Use-Type Lyophilized Lipid Nanoparticle Formulation for the Postencapsulation of Messenger RNA
ACS Nano·2023· 34 cited
Reactivation of Anticancer Immunity by Resetting Interorgan Crosstalk in Immune‐Suppressive Cells with a Nanoparticulated Anti‐Inflammatory Drug
Small·2023· 2 citedOpen Access
Delivering mRNA to Secondary Lymphoid Tissues by Phosphatidylserine‐Loaded Lipid Nanoparticles
Advanced Healthcare Materials·2022· 50 citedOpen Access
siRNA delivery to lymphatic endothelial cells via ApoE-mediated uptake by lipid nanoparticles
Journal of Controlled Release·2022· 27 cited
Delivery of aPD-L1 antibody to i.p. tumors via direct penetration by i.p. route: Beyond EPR effect
Journal of Controlled Release·2022· 13 cited
Development of siRNA Delivery System by Lipid Nanoparticles Modified with Functional Materials for Cancer Treatment
Biological and Pharmaceutical Bulletin·2022· 5 citedOpen Access
pH-Responsive Lipid Nanoparticles Achieve Efficient mRNA Transfection in Brain Capillary Endothelial Cells
Pharmaceutics·2022· 13 citedOpen Access
Targeted delivery of lipid nanoparticle to lymphatic endothelial cells via anti-podoplanin antibody
Journal of Controlled Release·2022· 36 cited
Novel antiangiogenic therapy targeting biglycan using tumor endothelial cell‐specific liposomal siRNA delivery system
Cancer Science·2022· 26 citedOpen Access
Improvement of mRNA Delivery Efficiency to a T Cell Line by Modulating PEG-Lipid Content and Phospholipid Components of Lipid Nanoparticles
Pharmaceutics·2021· 31 citedOpen Access
Proteomics Analysis of Lymphatic Metastasis-Related Proteins Using Highly Metastatic Human Melanoma Cells Originated by Sequential <i>in Vivo</i> Implantation
Biological and Pharmaceutical Bulletin·2021Open Access
Optimization of Sentinel Lymph Node Imaging Methodology Using Anionic Liposome and Hyaluronidase
Pharmaceutics·2021· 7 citedOpen Access
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Frequent Co-authors

Hideyoshi Harashima(19), Hidetaka Akita(15), Teruo Okano(12), Hiroto Hatakeyama(10), Kazunori Kataoka(8), Yusuke Sato(7), Hiroki Tanaka(7), M. Yokoyama(6), Yuta Nakai(6), Kota Tange(6), Mamoru Hyodo(5), Akira Ohtomo(3), Yuko Yoshida(3), Joo Eun Chung(3), Takao Aoyagi(3), Glen S. Kwon(3), Kyoko Hida(3), Tomoya Hada(3), Shoshiro Yamamoto(3), Wataru Mizumura(3)