Mauricio R. Alvira

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index4.7kcitations21works0.02yr avg
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Research Topics

Virus-based gene therapy research(16), Viral Infectious Diseases and Gene Expression in Insects(7), CRISPR and Genetic Engineering(4), CAR-T cell therapy research(4), Herpesvirus Infections and Treatments(3)

Publications21 total

Detection Assay for Replication-Competent Adenovirus by Concentration Passage and Real-Time Quantitative Polymerase Chain Reaction (qPCR)
Cold Spring Harbor Protocols·2019· 2 cited
Deamidation of Amino Acids on the Surface of Adeno-Associated Virus Capsids Leads to Charge Heterogeneity and Altered Vector Function
Molecular Therapy·2018· 114 citedOpen Access
90. Identification of an Adeno-Associated Virus Binding Epitope for AVB Sepharose Affinity Resin
Molecular Therapy·2015· 2 citedOpen Access
Identification of an adeno-associated virus binding epitope for AVB sepharose affinity resin
Molecular Therapy — Methods & Clinical Development·2015· 47 citedOpen Access
Manufacturing and Characterization of a Recombinant Adeno-Associated Virus Type 8 Reference Standard Material
Human Gene Therapy·2014· 87 citedOpen Access
Absolute Determination of Single-Stranded and Self-Complementary Adeno-Associated Viral Vector Genome Titers by Droplet Digital PCR
Human Gene Therapy Methods·2013· 163 citedOpen Access
Analysis of Particle Content of Recombinant Adeno-Associated Virus Serotype 8 Vectors by Ion-Exchange Chromatography
Human Gene Therapy Methods·2012· 95 citedOpen Access
Rapid, Simple, and Versatile Manufacturing of Recombinant Adeno-Associated Viral Vectors at Scale
Human Gene Therapy·2010· 326 citedOpen Access
Clades of Adeno-Associated Viruses Are Widely Disseminated in Human Tissues
Journal of Virology·2004· 1.0k citedOpen Access
High throughput creation of recombinant adenovirus vectors by direct cloning, green-white selection and I-Sce I-mediated rescue of circular adenovirus plasmids in 293 cells
Gene Therapy·2003· 37 cited
Adeno-associated viruses undergo substantial evolution in primates during natural infections
Proceedings of the National Academy of Sciences·2003· 321 citedOpen Access
Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy
Proceedings of the National Academy of Sciences·2002· 1.5k citedOpen Access
Replication-Defective Vector Based on a Chimpanzee Adenovirus
Journal of Virology·2001· 267 citedOpen Access
Kvβ Subunits Increase Expression of Kv4.3 Channels by Interacting with Their C Termini
Journal of Biological Chemistry·2001· 91 citedOpen Access
Genetic Studies Exposing the Splicing Events Involved in Herpes Simplex Virus Type 1 Latency-Associated Transcript Production during Lytic and Latent Infection
Journal of Virology·1999· 26 citedOpen Access
The impact of developmental stage, route of administration and the immune system on adenovirus-mediated gene transfer.
PubMed·1994· 216 cited
Expression of thyrotropin-releasing hormone receptors by adenovirus-mediated gene transfer reveals that thyrotropin-releasing hormone desensitization is cell specific.
Molecular Pharmacology·1994· 33 cited
Quantitative determination of adenovirus-mediated gene delivery to rat cardiac myocytes in vitro and in vivo.
Proceedings of the National Academy of Sciences·1993· 253 citedOpen Access
Characterization of the Mouse β<sup>maj</sup> Globin Transcription Termination Region: a Spacing Sequence is Required Between the Poly(A) Signal Sequence and Multiple Downstream Termination Elements
Molecular and Cellular Biology·1993· 21 cited
Characterization of the mouse beta maj globin transcription termination region: a spacing sequence is required between the poly(A) signal sequence and multiple downstream termination elements.
Molecular and Cellular Biology·1993· 52 citedOpen Access
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Frequent Co-authors

James M. Wilson(12), Martin Lock(8), Guangping Gao(6), Erik Falck-Pedersen(5), Roberto Calcedo(3), Luk H. Vandenberghe(3), You Lü(2), Xiangyang Zhou(2), John J. Rux(2), A Kass-Eisler(2), Peter M. Buttrick(2), Leslie A. Leinwand(2), Jogiraju Tantravahi(2), Qiang Wang(2), Andrew Prongay(2), Boris Petkov(2), Lili Wang(1), Julie Johnston(1), Arabinda Samanta(1), Jaan Toelen(1)