Martin Lock

Withernsea Hospital — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

19h-index2.0kcitations40works0.02yr avg
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Research Topics

Virus-based gene therapy research(30), Viral Infectious Diseases and Gene Expression in Insects(17), CRISPR and Genetic Engineering(7), Herpesvirus Infections and Treatments(6), Viral gastroenteritis research and epidemiology(5)

Publications40 total

Significant Differences in Capsid Properties and Potency Between Adeno-Associated Virus Vectors Produced in Sf9 and HEK293 Cells
Human Gene Therapy·2023· 16 cited
Pelvic tilt in sitting: Do you see what I see? (Maybe not)
New Zealand Journal of Physiotherapy·2023Open Access
Characterization of a Recombinant Adeno-Associated Virus Type 2 Reference Standard Material
UNC Libraries·2020Open Access
Sensitive Determination of Infectious Titer of Recombinant Adeno-Associated Viruses (rAAVs) Using TCID<sub>50</sub> End-Point Dilution and Quantitative Polymerase Chain Reaction (qPCR)
Cold Spring Harbor Protocols·2020· 8 cited
Detection Assay for Replication-Competent Adenovirus by Concentration Passage and Real-Time Quantitative Polymerase Chain Reaction (qPCR)
Cold Spring Harbor Protocols·2019· 2 cited
Measuring the Infectious Titer of Recombinant Adenovirus Using Tissue Culture Infection Dose 50% (TCID<sub>50</sub>) End-Point Dilution and Quantitative Polymerase Chain Reaction (qPCR)
Cold Spring Harbor Protocols·2019· 21 cited
Preparation of a DNA Standard for Quantitative Polymerase Chain Reaction (qPCR)
Cold Spring Harbor Protocols·2019· 4 cited
Stability of the adeno-associated virus 8 reference standard material
Gene Therapy·2019· 15 cited
Deamidation of Amino Acids on the Surface of Adeno-Associated Virus Capsids Leads to Charge Heterogeneity and Altered Vector Function
Molecular Therapy·2018· 114 citedOpen Access
699. Effective AAV9 Vector Delivery to Nasal Mucosa for Protection Against Airborne Challenge with Influenza A and B
Molecular Therapy·2016Open Access
90. Identification of an Adeno-Associated Virus Binding Epitope for AVB Sepharose Affinity Resin
Molecular Therapy·2015· 2 citedOpen Access
Identification of an adeno-associated virus binding epitope for AVB sepharose affinity resin
Molecular Therapy — Methods & Clinical Development·2015· 47 citedOpen Access
Manufacturing and Characterization of a Recombinant Adeno-Associated Virus Type 8 Reference Standard Material
Human Gene Therapy·2014· 87 citedOpen Access
Absolute Determination of Single-Stranded and Self-Complementary Adeno-Associated Viral Vector Genome Titers by Droplet Digital PCR
Human Gene Therapy Methods·2013· 163 citedOpen Access
Biodistribution of AAV8 Vectors Expressing Human Low-Density Lipoprotein Receptor in a Mouse Model of Homozygous Familial Hypercholesterolemia
Human Gene Therapy Clinical Development·2013· 44 citedOpen Access
Adeno-associated Viruses as Liver-Directed Gene Delivery Vehicles: Focus on Lipoprotein Metabolism
Methods in molecular biology·2013· 24 cited
A1-8 Reference materials for the characterization of adeno-associated viral vectors
2012
A1-8 Reference materials for the characterization of adeno-associated viral vectors
2012· 1 cited
Analysis of Particle Content of Recombinant Adeno-Associated Virus Serotype 8 Vectors by Ion-Exchange Chromatography
Human Gene Therapy Methods·2012· 95 citedOpen Access
Safety and Immunogenicity of LC16m8, an Attenuated Smallpox Vaccine in Vaccinia-Naive Adults
The Journal of Infectious Diseases·2011· 103 citedOpen Access
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Frequent Co-authors

James M. Wilson(21), Guangping Gao(9), Mauricio R. Alvira(8), Michael T. Korn(6), Eduard Ayuso(6), Luk H. Vandenberghe(5), Fátima Bosch(5), Christophe Darmon(5), Philippe Moullier(5), Richard O. Snyder(5), Peter Bell(4), Véronique Blouin(4), Miguel Sena‐Esteves(4), Jaan Toelen(3), Zeger Debyser(3), You Lü(3), Roberto Calcedo(3), Nigel W. Fraser(3), Shu‐Jen Chen(3), Susan P. McGorray(3)