Brian M. Wyvratt

Engineering · Physical Sciences

7h-index211citations17works3.02yr avg
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Research Topics

Process Optimization and Integration(5), Innovative Microfluidic and Catalytic Techniques Innovation(5), Analytical Chemistry and Chromatography(3), Catalysis and Hydrodesulfurization Studies(3), Crystallization and Solubility Studies(3)

Publications17 total

A Comparative Study of Strategies for Incorporating Uncertainty in Design Space Determination for Pharmaceutical Manufacturing
Industrial & Engineering Chemistry Research·2025
Integrating Functional Principal Component Analysis with Data-Rich Experimentation for Enhanced Drug Substance Development
Organic Process Research & Development·2024· 7 cited
Process knowledge for drug substance production <i>via</i> kinetic modeling, parameter estimability analysis and reaction optimization
Reaction Chemistry & Engineering·2024· 2 cited
Use of a Dynamic Flow Platform To Translate a Batch Immobilized Transaminase Process to a Packed Bed Reactor for the Synthesis of an Intermediate of Nemtabrutinib
Organic Process Research & Development·2023· 13 cited
Parameter estimation and estimability analysis in pharmaceutical models with uncertain inputs
AIChE Journal·2023· 10 citedOpen Access
Parameter Estimation and Estimability Analysis in Pharmaceutical Models with Uncertain Inputs
2023· 1 citedOpen Access
Automated Optimization under Dynamic Flow Conditions
2022Open Access
Automated optimization under dynamic flow conditions
Reaction Chemistry & Engineering·2022· 23 cited
Automated Optimization under Dynamic Flow Conditions
2022· 2 citedOpen Access
Development of an Efficient Route to 2-Ethynylglycerol for the Synthesis of Islatravir
2021· 4 citedOpen Access
Development of an Efficient Route to 2-Ethynylglycerol for the Synthesis of Islatravir
2021· 2 citedOpen Access
Multidimensional dynamic experiments for data-rich process development of reactions in flow
Reaction Chemistry & Engineering·2019· 42 cited
Reactivity of Hydrogen on and in Nanostructured Molybdenum Nitride: Crotonaldehyde Hydrogenation
ACS Catalysis·2016· 57 citedOpen Access
Characterization of Structural and Electronic Transitions During Reduction and Oxidation of Ru(acac)<sub>3</sub> Flow Battery Electrolytes by using X‐ray Absorption Spectroscopy
ChemElectroChem·2016· 8 citedOpen Access
Examination of Property-Reactivity Relationships of Early Transition Metal Carbides and Nitrides as Catalysts and Catalytic Supports
Deep Blue (University of Michigan)·2016Open Access
Effects of passivation on synthesis, structure and composition of molybdenum carbide supported platinum water–gas shift catalysts
Journal of Catalysis·2015· 39 citedOpen Access
Investigations of the Chemistry of Early Transition-Metal Nitrides/Carbides for Hydrogenation/Dehydrogenation Reactions
24th North American Catalysis Society Meeting·2015· 1 cited

Frequent Co-authors

Jonathan P. McMullen(10), Iman Moshiritabrizi(4), Kimberley B. McAuley(4), Jason R. Gaudet(3), Levi T. Thompson(3), Jeffrey T. Kuethe(3), Kevin M. Maloney(3), Ji Qi(3), Shane T. Grosser(2), Kaveh Abdi(2), Stephan M. Rummelt(2), James F. Dropinski(2), Gregory Hughes(2), Donghong Li(2), Eric L. Margelefsky(2), Rose Mathew(2), Daniel J. Muzzio(2), Christopher C. Nawrat(2), Justin A. Newman(2), Honggui Ouyang(2)