Carla Scali

Kedrion (Italy) — Italy

Medicine · Health Sciences

29h-index3.7kcitations76works7.02yr avg
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Research Topics

Cholinesterase and Neurodegenerative Diseases(27), Neuroscience and Neuropharmacology Research(21), Nicotinic Acetylcholine Receptors Study(20), Alzheimer's disease research and treatments(13), Memory and Neural Mechanisms(10)

Publications76 total

New orphan disease therapies from the proteome of industrial plasma processing waste- a treatment for aceruloplasminemia
Communications Biology·2024· 7 citedOpen Access
Human Intravenous Immunoglobulin Alleviates Neuropathic Symptoms in a Rat Model of Paclitaxel-Induced Peripheral Neurotoxicity
International Journal of Molecular Sciences·2021· 24 citedOpen Access
High-dose intravenous immunoglobulins reduce nerve macrophage infiltration and the severity of bortezomib-induced peripheral neurotoxicity in rats
Journal of Neuroinflammation·2018· 55 citedOpen Access
The Role of Cholinergic System in Novel Object Recognition
Handbook of behavioral neuroscience·2018· 2 cited
Ivig Effect In A Wistar Rat Model Of Bortezomib-Induced Peripheral Neuropathy
BOA (University of Milano-Bicocca)·2017
Intravenous Immunoglobulin Preparation Attenuates Pain Behaviors in a Wistar Rat Model of Bortezomib-Induced Peripheral Neuropathy
BOA (University of Milano-Bicocca)·2017
Multimodal molecular imaging system for pathway-specific reporter gene expression
European Journal of Pharmaceutical Sciences·2016· 3 cited
Pharmacokinetics of IVIg in Wistar rats
BOA (University of Milano-Bicocca)·2016
Recombinant Adeno Associated Viral (AAV) vector type 9 delivery of Ex1-Q138-mutant huntingtin in the rat striatum as a short-time model for in vivo studies in drug discovery
Neurobiology of Disease·2015· 12 citedOpen Access
siRNA screen identifies QPCT as a druggable target for Huntington's disease
Nature Chemical Biology·2015· 93 citedOpen Access
A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease
Human Molecular Genetics·2014· 141 citedOpen Access
Fused 3-Hydroxy-3-trifluoromethylpyrazoles Inhibit Mutant Huntingtin Toxicity
ACS Medicinal Chemistry Letters·2013· 12 citedOpen Access
Morphometrical evaluation of neurodegeneration: an integrated multiparametric approach using whole slide imaging
2013Open Access
<i>N</i>-[5-(5-Fluoropyridin-3-yl)-1<i>H</i>-pyrazol-3-yl]-4-piperidin-1-ylbutyramide (SEN78702, WYE-308775): A Medicinal Chemistry Effort toward an α7 Nicotinic Acetylcholine Receptor Agonist Preclinical Candidate
Journal of Medicinal Chemistry·2012· 14 citedOpen Access
Discovery of a Novel Alpha-7 Nicotinic Acetylcholine Receptor Agonist Series and Characterization of the Potent, Selective, and Orally Efficacious Agonist 5-(4-Acetyl[1,4]diazepan-1-yl)pentanoic Acid [5-(4-Methoxyphenyl)-1H-pyrazol-3-yl] Amide (SEN15924, WAY-361789)
Journal of Medicinal Chemistry·2012· 26 citedOpen Access
Preclinical assessment of an adjunctive treatment approach for cognitive impairment associated with schizophrenia using the alpha7 nicotinic acetylcholine receptor agonist WYE-103914/SEN34625
Psychopharmacology·2011· 20 cited
VSTM2L is a novel secreted antagonist of the neuroprotective peptide Humanin
The FASEB Journal·2011· 29 cited
Intrastriatal viral vector delivery of mutant huntingtin as rat model of Huntington’s Disease
2011
Recombinant Adeno Associated Viral (AAV) vector delivery of mutant huntingtin as rat model for in vitro and in vivo studies.
CINECA IRIS Institutial research information system (University of Pisa)·2011
Viral vector delivery of mutant huntingtin as model of huntington's disease in the rat: in vivo and in vitro study
CINECA IRIS Institutial research information system (University of Pisa)·2011
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Frequent Co-authors

Giancarlo Pepeu(32), Fiorella Casamenti(28), Costanza Prosperi(13), Maria Grazia Giovannini(8), Andrea Caricasole(7), Lisa Giovannelli(7), Arianna Bellucci(6), Georg C. Terstappen(6), Giuseppe Pollio(6), Renza Roncarati(6), Thomas A. Comery(6), Chiara Ghiron(6), Simon N. Haydar(6), John Dunlop(6), Marco Gianfriddo(5), Michela Valacchi(5), Maria Giuliana Vannucchi(4), Enrica Diodato(4), Arianna Nencini(4), Ilaria Ceccarelli(4)