Thomas J. McCorvie

Energy Biosciences Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index1.0kcitations49works4.72yr avg
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Research Topics

Metabolism and Genetic Disorders(31), Folate and B Vitamins Research(10), Biochemical and Molecular Research(9), Enzyme Structure and Function(8), Amino Acid Enzymes and Metabolism(8)

Publications49 total

5,10-Methylenetetrahydrofolate Reductase─the Key Allosteric Regulator in One-Carbon Metabolism
Biochemistry·2026Open Access
Structural insights into cobalamin loading and reactivation of human methionine synthase
2025Open Access
Bi-allelic <i>ATG12</i> variants impair autophagy and cause a neurodevelopmental disorder
2025Open Access
Scientific Business Abstracts
QJM·2024Open Access
Dynamic inter-domain transformations mediate the allosteric regulation of human 5, 10-methylenetetrahydrofolate reductase
Nature Communications·2024· 12 citedOpen Access
Architecture and regulation of filamentous human cystathionine beta-synthase
Nature Communications·2024· 16 citedOpen Access
Novel homozygous variants in PRORP expand the genotypic spectrum of combined oxidative phosphorylation deficiency 54
European Journal of Human Genetics·2023· 7 citedOpen Access
Dynamic inter-domain transformations mediate the allosteric regulation of human 5, 10-methylenetetrahydrofolate reductase
2023· 1 citedOpen Access
Novel homozygous variants in PRORP expand the genotypic spectrum of combined oxidative phosphorylation deficiency 54
2023Open Access
Architecture and regulation of filamentous human cystathionine beta-synthase
2023· 3 citedOpen Access
The complex machinery of human cobalamin metabolism
Journal of Inherited Metabolic Disease·2023· 27 citedOpen Access
Obituary for Professor David Julian Timson, <scp>PhD</scp>
Journal of Inherited Metabolic Disease·2022
Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphate
Nature Structural & Molecular Biology·2022· 48 citedOpen Access
Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphate
2021· 6 citedOpen Access
Galactosemia: Towards Pharmacological Chaperones
Journal of Personalized Medicine·2021· 19 citedOpen Access
Dehydrogenase E1 and transketolase domain-containing protein 1 (DHTKD1); A Target Enabling Package
Zenodo (CERN European Organization for Nuclear Research)·2020Open Access
Dehydrogenase E1 and transketolase domain-containing protein 1 (DHTKD1); A Target Enabling Package
Zenodo (CERN European Organization for Nuclear Research)·2020Open Access
Dehydrogenase E1 and transketolase domain-containing protein 1 (DHTKD1); A Target Enabling Package
Figshare·2020Open Access
Dehydrogenase E1 and transketolase domain-containing protein 1 (DHTKD1); A Target Enabling Package
Zenodo (CERN European Organization for Nuclear Research)·2020Open Access
Crystal structure and interaction studies of human DHTKD1 provide insight into a mitochondrial megacomplex in lysine catabolism
IUCrJ·2020· 25 citedOpen Access
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Frequent Co-authors

Wyatt W. Yue(29), David J. Timson(14), J. Kopec(12), G.A. Bezerra(10), William R. Foster(10), D. Sean Froese(9), Fiona Fitzpatrick(9), Claire Strain‐Damerell(9), H. Bailey(8), Sabrina MacKinnon(7), Kevin G. Hicks(5), Sven W. Sauer(5), Bianca Dimitrov(5), Jared Rutter(5), Stefan Kölker(5), Arnaud Baslé(5), Minghao Zhang(5), Manshu Tang(5), M. Fairhead(5), Anthony Tumber(5)