Jana Kašpárková

Czech Academy of Sciences — Czech Republic

Medicine · Health Sciences

49h-index7.9kcitations257works5.42yr avg
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Research Topics

Metal complexes synthesis and properties(157), Ferrocene Chemistry and Applications(81), DNA and Nucleic Acid Chemistry(80), Crystallization and Solubility Studies(46), X-ray Diffraction in Crystallography(46)

Publications257 total

Platinum(IV) oxaliplatin analog containing axial benzoate ligands induces mitochondrial hyperpolarization and caspase-dependent apoptosis in pancreatic cancer cell models
Chemico-Biological Interactions·2025
Phototoxicity of Half-Sandwich Rhodium(III) Complexes with Anthracene and Biphenyl Substituents toward Mammalian Cancer Cells and Multicellular Tumor Spheroids
Journal of Medicinal Chemistry·2025· 2 citedOpen Access
Excited-State <i>Cis</i> and <i>Trans</i> Pt(IV) Diamine Anticancer Complexes
Inorganic Chemistry·2025· 2 citedOpen Access
A novel benzothiazole-1,2,3-triazole-based arene osmium(<scp>ii</scp>) complex as an effective rhabdomyosarcoma cancer stem cell agent
Inorganic Chemistry Frontiers·2025· 8 citedOpen Access
A Novel Substituted Benzo[<i>g</i>]quinoxaline-Based Cyclometalated Ru(II) Complex as a Biocompatible Membrane-Targeted PDT Colon Cancer Stem Cell Agent
Journal of Medicinal Chemistry·2024· 10 citedOpen Access
Antimetastatic activity of (arene)ruthenium(II) complex of 4-aryl-4H-naphthopyran
Chemico-Biological Interactions·2024· 2 cited
Multiaction Pt(IV) Prodrugs Releasing Cisplatin and Dasatinib Are Potent Anticancer and Anti-Invasive Agents Displaying Synergism between the Two Drugs
Journal of Medicinal Chemistry·2024· 8 cited
Photoactivatable, mitochondria targeting dppz iridium(III) complex selectively interacts and damages mitochondrial DNA in cancer cells
Chemico-Biological Interactions·2024· 5 cited
New cyclometalated Ru(<scp>ii</scp>) polypyridyl photosensitizers trigger oncosis in cancer cells by inducing damage to cellular membranes
Inorganic Chemistry Frontiers·2024· 12 citedOpen Access
Novel 2-(5-Arylthiophen-2-yl)-benzoazole Cyclometalated Iridium(III) dppz Complexes Exhibit Selective Phototoxicity in Cancer Cells by Lysosomal Damage and Oncosis
Journal of Medicinal Chemistry·2023· 45 citedOpen Access
N-Indolyl diiron vinyliminium complexes exhibit antiproliferative effects in cancer cells associated with disruption of mitochondrial homeostasis, ROS scavenging, and antioxidant activity
Chemico-Biological Interactions·2023· 13 citedOpen Access
Multitargeting Prodrugs that Release Oxaliplatin, Doxorubicin and Gemcitabine are Potent Inhibitors of Tumor Growth and Effective Inducers of Immunogenic Cell Death
Angewandte Chemie International Edition·2023· 41 citedOpen Access
Multitargeting Prodrugs that Release Oxaliplatin, Doxorubicin and Gemcitabine are Potent Inhibitors of Tumor Growth and Effective Inducers of Immunogenic Cell Death
Angewandte Chemie·2023Open Access
Palladium and Platinum Complexes of the Antimetabolite Fludarabine with Vastly Enhanced Selectivity for Tumour over Non-Malignant Cells
Molecules·2023· 9 citedOpen Access
Platinum(IV) Derivatives of [Pt(1<i>S</i>,2<i>S</i>-diaminocyclohexane)(5,6-dimethyl-1,10-phenanthroline)] with Diclofenac Ligands in the Axial Positions: A New Class of Potent Multi-action Agents Exhibiting Selectivity to Cancer Cells
Journal of Medicinal Chemistry·2023· 15 citedOpen Access
CCDC 2226215: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
Cyclometalated Benzimidazole Osmium(II) Complexes with Antiproliferative Activity in Cancer Cells Disrupt Calcium Homeostasis
Inorganic Chemistry·2023· 12 citedOpen Access
Anticancer gallium(III) complexes with halogen- and nitroderivatives of 8- hydroxyquinoline
2023
CCDC 2167602: Experimental Crystal Structure Determination
The Cambridge Structural Database·2022Open Access
CCDC 2167597: Experimental Crystal Structure Determination
The Cambridge Structural Database·2022Open Access
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Frequent Co-authors

Viktor Brabec(50), Vojtěch Novohradský(14), Olga Nováková(12), Peter J. Sadler(10), Oldřich Vrána(10), Nicholas P. Farrell(10), Hana Kostrhunová(8), Giovanni Natile(8), Jitka Prachařová(6), Dan Gibson(6), Lenka Zerzánková(5), Jana Štěpánková(5), Gloria Vigueras(4), José Ruiz(4), Jaroslav Malina(4), Julie A. Woods(3), Pavla Heringová(3), Lenka Marková(3), Marie Vojtı́šková(3), Raji Raveendran(3)