Oldřich Vrána

Czech Academy of Sciences, Institute of Biophysics — Czech Republic

Medicine · Health Sciences

28h-index2.8kcitations72works0.02yr avg
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Research Topics

Metal complexes synthesis and properties(48), DNA and Nucleic Acid Chemistry(32), Ferrocene Chemistry and Applications(25), Electrochemical Analysis and Applications(7), Advanced biosensing and bioanalysis techniques(6)

Publications72 total

Correction: Simultaneous delivery of olaparib and carboplatin in PEGylated liposomes imparts this drug combination hypersensitivity and selectivity for breast tumor cells
Oncotarget·2018· 3 citedOpen Access
Simultaneous delivery of olaparib and carboplatin in PEGylated liposomes imparts this drug combination hypersensitivity and selectivity for breast tumor cells
Oncotarget·2018· 26 citedOpen Access
Enhancing Tumor Cell Response to Chemotherapy through the Targeted Delivery of Platinum Drugs Mediated by Highly Stable, Multifunctional Carboxymethylcellulose‐Coated Magnetic Nanoparticles
Chemistry - A European Journal·2016· 15 cited
Internalization of Ineffective Platinum Complex in Nanocapsules Renders It Cytotoxic
Chemistry - A European Journal·2016· 14 cited
Comment on “Delivering a photosensitive transplatin prodrug to overcome cisplatin drug resistance” by H. Song, W. Li, R. Qi, L. Yan, X. Jing, M. Zheng and H. Xiao, Chem. Commun., 2015, <b>51</b>, 11493
Chemical Communications·2016· 6 cited
Potentiation of mitochondrial dysfunction in tumor cells by conjugates of metabolic modulator dichloroacetate with a Pt(IV) derivative of oxaliplatin
Journal of Inorganic Biochemistry·2015· 60 cited
New insights into the molecular and epigenetic effects of antitumor Pt(IV)-valproic acid conjugates in human ovarian cancer cells
Biochemical Pharmacology·2015· 90 cited
Antitumor platinum(IV) derivatives of oxaliplatin with axial valproato ligands
Journal of Inorganic Biochemistry·2014· 76 cited
Analysis of DNA modified by cerium (III), lanthanum (III) and gadolinium (III) ions by using of raman spectroscopy
Journal Of Biochemical Technology·2014· 2 cited
Conformation and recognition of DNA damaged by antitumor cis-dichlorido platinum(II) complex of CDK inhibitor bohemine
European Journal of Medicinal Chemistry·2014· 11 cited
The Study of Naphthoquinones and Their Complexes with DNA by Using Raman Spectroscopy and Surface Enhanced Raman Spectroscopy: New Insight into Interactions of DNA with Plant Secondary Metabolites
BioMed Research International·2014· 16 citedOpen Access
Insight into the toxic effects of cis-dichloridoplatinum(II) complexes containing 7-azaindole halogeno derivatives in tumor cells
JBIC Journal of Biological Inorganic Chemistry·2013· 25 cited
Mechanistic insights into toxic effects of a benzotriazolate-bridged dinuclear platinum(II) compound in tumor cells
Inorganica Chimica Acta·2012· 10 cited
Unique DNA Binding Mode of Antitumor Trinuclear Tridentate Platinum(II) Compound
Molecular Pharmaceutics·2011· 26 cited
Organometallic Half-Sandwich Iridium Anticancer Complexes
Journal of Medicinal Chemistry·2011· 348 citedOpen Access
Different Features of the DNA Binding Mode of Antitumor<i>cis</i>-Amminedichlorido(cyclohexylamine)platinum(II) (JM118) and Cisplatin in Vitro
Chemical Research in Toxicology·2010· 22 cited
Cytotoxicity, cellular uptake, glutathione and DNA interactions of an antitumor large-ring PtII chelate complex incorporating the cis-1,4-diaminocyclohexane carrier ligand
Biochemical Pharmacology·2009· 54 citedOpen Access
Conformation and recognition of DNA modified by a new antitumor dinuclear PtII complex resistant to decomposition by sulfur nucleophiles
Biochemical Pharmacology·2009· 30 citedOpen Access
Mechanistic studies of the modulation of cleavage activity of topoisomerase I by DNA adducts of mono- and bi-functional PtII complexes
Nucleic Acids Research·2009· 16 citedOpen Access
CCDC 681045: Experimental Crystal Structure Determination
The Cambridge Structural Database·2009Open Access
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Frequent Co-authors

Viktor Brabec(44), Jana Kašpárková(23), Olga Nováková(13), V. Kleinwächter(7), Vojtěch Novohradský(7), Nicholas P. Farrell(6), Lenka Zerzánková(5), Tereza Suchánková(5), Anna Halámiková(4), Dan Gibson(4), Valentina I. Kiseleva(4), Giovanni Natile(4), Abraha Habtemariam(3), Jana Štěpánková(3), Raji Raveendran(3), Juraj Zajac(3), Radana Olivová(3), Peter J. Sadler(2), Paul M. van Vliet(2), J. Reedijk(2)