E O’Brien

University College Dublin — Ireland

Medicine · Health Sciences

36h-index6.2kcitations161works0.62yr avg
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Research Topics

Blood Pressure and Hypertension Studies(33), Lung Cancer Treatments and Mutations(17), Lung Cancer Diagnosis and Treatment(11), Cardiovascular Health and Disease Prevention(11), Hemodynamic Monitoring and Therapy(11)

Publications160 total

Pleural liquid biopsy: A non-invasive adjunct to tissue biopsy for molecular profiling
2025
Lung Health Check pilot: Ireland’s flagship lung cancer screening trial
BMJ Open Respiratory Research·2025· 2 citedOpen Access
Protocol for a Cohort Study on Lung Cancer Diagnostic Pathways and Outcomes in Ireland
HRB Open Research·2025· 1 citedOpen Access
Liquid biopsy in lung cancer
Breathe·2025· 1 citedOpen Access
Clinical benefit and cost of plasma-first next-generation sequencing in patients with newly diagnosed advanced non-small cell lung cancer in Ireland: The PLAN study
European Journal of Cancer·2025
Cost and resource utilisation for liquid biopsy vs tissue biopsy genotyping in advanced NSCLC: A micro-costing model.
Journal of Clinical Oncology·2025
Characteristics of Malignant Pleural Effusions Presenting to a Tertiary Irish Hospital and the Need for Non-invasive Diagnostic Techniques
American Journal of Respiratory and Critical Care Medicine·2025
Comparison of the WatchPAT device with Polysomnography and Home Limited Sleep Studies for the Diagnosis of Obstructive Sleep Apnoea.
2024
40P Lorlatinib-associated weight gain and dyslipidaemia: A single centre UK experience
ESMO Open·2024· 1 citedOpen Access
120MO Adjuvant pembrolizumab versus placebo for early-stage NSCLC after resection and optional chemotherapy: Updated results from PEARLS/KEYNOTE-091
Immuno-Oncology Technology·2023· 11 citedOpen Access
VP228 Post-hoc analyses of prednisolone use and hepatotoxicity in clinical trials of intravenous onasemnogene abeparvovec
Neuromuscular Disorders·2023
Tracheostomy insertion in COVID-19: insertion practice and factors leading to unplanned tube exchange
Journal of Thoracic Disease·2023· 3 citedOpen Access
1541P Real-world data of atezolizumab plus carboplatin-etoposide for patients with extensive stage SCLC: The UK experience
Annals of Oncology·2022· 5 citedOpen Access
930MO PD-L1 expression and outcomes of pembrolizumab and placebo in completely resected stage IB-IIIA NSCLC: Subgroup analysis of PEARLS/KEYNOTE-091
Annals of Oncology·2022· 8 citedOpen Access
Results of screening in early and advanced thoracic malignancies in the EORTC pan-European SPECTAlung platform
Scientific Reports·2022· 4 citedOpen Access
Exhaled Breath Condensate (EBC) analysis of circulating tumour DNA (ctDNA) using a lung cancer specific UltraSEEK oncogene panel
Lung Cancer·2022· 17 cited
C3d Triggers Neutrophil Degranulation And Decreases Endothelial Cell Migration, with Implications for Patients with Alpha-1 Antitrypsin Deficiency
2022
VP3-2022: Pembrolizumab (pembro) versus placebo for early-stage non-small cell lung cancer (NSCLC) following complete resection and adjuvant chemotherapy (chemo) when indicated: Randomized, triple-blind, phase III EORTC-1416-LCG/ETOP 8-15 – PEARLS/KEYNOTE-091 study
Annals of Oncology·2022· 71 cited
A Review of Alpha-1 Antitrypsin Binding Partners for Immune Regulation and Potential Therapeutic Application
International Journal of Molecular Sciences·2022· 75 citedOpen Access
C3d Elicits Neutrophil Degranulation and Decreases Endothelial Cell Migration, with Implications for Patients with Alpha-1 Antitrypsin Deficiency
Biomedicines·2021· 5 citedOpen Access
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Frequent Co-authors

Noel G. McElvaney(9), Emer P. Reeves(6), Ross Morgan(5), Killian Hurley(5), Tomás P. Carroll(4), Cormac McCarthy(4), Oliver J. McElvaney(3), Imran Sulaiman(3), Cedric Gunaratnam(3), Richard W. Costello(3), Eoghan de Barra(3), K O'Malley(3), Martin Clynes(3), Paula Meleady(3), Michael Henry(3), Alexey Bulychev(3), Marvin J. Miller(3), Shahriar Mobashery(3), Oisín F. McElvaney(2), Mark P. Murphy(2)