Zachary E. X. Dance

Merck & Co., Inc., Rahway, NJ, USA (United States) — United States

Materials Science · Physical Sciences

11h-index1.1kcitations29works10.72yr avg
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Research Topics

Crystallization and Solubility Studies(9), Photochemistry and Electron Transfer Studies(5), X-ray Diffraction in Crystallography(5), Enzyme Catalysis and Immobilization(4), interferon and immune responses(4)

Publications29 total

Direct Injection Mass Spectrometry and iFishMass for the High-Throughput Analysis of Antibody Modifications
ACS Pharmacology & Translational Science·2025Open Access
Harnessing the Power of Chemometric Modeling and Plate Readers for High-Throughput Analysis of Biocatalytic Reactions
Analytical Chemistry·2025
Development of a Thiophosphorylation Process for the Synthesis of 2′F-Thio-Adenosine Monophosphate
Organic Process Research & Development·2024· 1 cited
Evolution of a Green and Sustainable Manufacturing Process for Belzutifan: Part 4─Applications of Process Analytical Technology in Heterogeneous Biocatalytic Hydroxylation
Organic Process Research & Development·2024· 11 cited
Engineering Hydroxylase Activity, Selectivity, and Stability for a Scalable Concise Synthesis of a Key Intermediate to Belzutifan
Angewandte Chemie·2024· 1 cited
Engineering Hydroxylase Activity, Selectivity, and Stability for a Scalable Concise Synthesis of a Key Intermediate to Belzutifan
Angewandte Chemie International Edition·2024· 51 citedOpen Access
Development of a Kilogram-Scale Synthesis of a Key Ulevostinag Subunit Part II: An Electrophilic Approach to Fluorinated Nucleosides
Organic Process Research & Development·2023· 4 cited
Gefapixant Citrate (MK-7264) Sulfonamide Step Speciation Study: Investigation into Precipitation–Dissolution Events during Addition of Chlorosulfonic Acid
Organic Process Research & Development·2023· 2 cited
CCDC 2007024: Experimental Crystal Structure Determination
The Cambridge Structural Database·2022Open Access
CCDC 2007023: Experimental Crystal Structure Determination
The Cambridge Structural Database·2022Open Access
CCDC 2007022: Experimental Crystal Structure Determination
The Cambridge Structural Database·2022Open Access
Diverse Catalytic Reactions for the Stereoselective Synthesis of Cyclic Dinucleotide MK-1454
Journal of the American Chemical Society·2022· 45 cited
A kinase-cGAS cascade to synthesize a therapeutic STING activator
Nature·2022· 125 cited
CCDC 2051778: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
CCDC 2051779: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
Manufacturing Process Development for Belzutifan, Part 4: Nitrogen Flow Criticality for Transfer Hydrogenation Control
Organic Process Research & Development·2021· 26 cited
Development of a Practical Manufacturing Process to Relebactam via Thorough Understanding of the Origin and Control of Oligomeric Impurities
Organic Process Research & Development·2021· 5 cited
Discovery and Development of an Unusual Organocatalyst for the Conversion of Thymidine to Furanoid Glycal
Organic Process Research & Development·2021· 6 cited
Investigation of Lithium Acetyl Phosphate Synthesis Using Process Analytical Technology
Organic Process Research & Development·2021· 14 cited
Quantitative Perspective on Online Flow Reaction Profiling Using a Miniature Mass Spectrometer
Organic Process Research & Development·2020· 3 cited
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Frequent Co-authors

Jennifer V. Obligacion(7), Andrew P. J. Brunskill(7), Nastaran Salehi Marzijarani(6), Jungchul Kim(6), Michael R. Wasielewski(5), Zhijian Liu(5), Patrick S. Fier(5), Joseph P. Smith(5), Benjamin D. Sherry(5), John A. McIntosh(4), Feng Peng(4), Matthew S. Winston(4), Xiaodong Bu(4), Joshua N. Kolev(4), Weilan Pan(4), Stephanus Axnanda(4), Rekha Gangam(4), Keith Mattern(4), Cheol K. Chung(4), Jacob H. Waldman(4)