Lukas K. Tamm

University of Virginia Health System — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

74h-index17.3kcitations312works5.42yr avg
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Research Topics

Lipid Membrane Structure and Behavior(206), Cellular transport and secretion(87), Protein Structure and Dynamics(43), RNA and protein synthesis mechanisms(35), Influenza Virus Research Studies(27)

Publications310 total

DeFrND: detergent-free reconstitution into native nanodiscs with designer membrane scaffold peptides
Nature Communications·2025· 3 citedOpen Access
Synaptophysin accelerates synaptic vesicle fusion by expanding the membrane upon neurotransmitter loading
Science Advances·2025· 5 citedOpen Access
BPS2025 - The two SNARE motifs of the neuronal SNARE SNAP25 have distinct, yet interdependent, regulatory roles in SNARE assembly and membrane fusion
Biophysical Journal·2025
BPS2025 - Munc18 and membrane lipids cooperate to regulate the lateral distribution of syntaxin-1a in the plasma membrane
Biophysical Journal·2025
BPS2025 - Investigating protein and lipid organizers of plasma membrane SNARE protein assembly
Biophysical Journal·2025
BPS2025 - Lipid-protein interactions play a crucial role in the HIV-1 fusion restriction mediated by Serinc5
Biophysical Journal·2025
BPS2025 - The two SNARE motifs of the neuronal SNARE SNAP25 have distinct, yet interdependent, regulatory roles in SNARE assembly and membrane fusion
Biophysical Journal·2025
Functionally distinct SNARE motifs of SNAP25 cooperate in SNARE assembly and membrane fusion
Biophysical Journal·2024· 8 citedOpen Access
Endosomal fusion of pH-dependent enveloped viruses requires ion channel TRPM7
Nature Communications·2024· 14 citedOpen Access
Sculpting conducting nanopore size and shape through de novo protein design
Science·2024· 40 citedOpen Access
Ca2+-mediated synaptotagmin C2 domain binding to target membranes changes the physical properties of the lipid bilayer
Biophysical Journal·2024
The two SNARE motifs of SNAP25 are structurally and functionally distinct
Biophysical Journal·2024Open Access
The role of Munc18 in regulating the spatial arrangement of Syntaxin-1A and SNARE complex assembly
Biophysical Journal·2024Open Access
Sculpting conducting nanopore size and shape through <i>de novo</i> protein design
2023· 5 citedOpen Access
Membrane lipids couple synaptotagmin to SNARE-mediated granule fusion in insulin-secreting cells
Molecular Biology of the Cell·2023· 5 citedOpen Access
Mechanisms of SNARE proteins in membrane fusion
Nature Reviews Molecular Cell Biology·2023· 188 citedOpen Access
Viral Membrane Fusion: A Dance Between Proteins and Lipids
Annual Review of Virology·2023· 76 citedOpen Access
A novel <i>in vitro</i> system of supported planar endosomal membranes (SPEMs) reveals an enhancing role for cathepsin B in the final stage of Ebola virus fusion and entry
Microbiology Spectrum·2023· 12 citedOpen Access
Serinc5 Restricts HIV Membrane Fusion by Altering Lipid Order and Heterogeneity in the Viral Membrane
ACS Infectious Diseases·2023· 21 citedOpen Access
Lipid-mediated interplay between host restriction factor Serinc5 and HIV-1 ENV glycoprotein
Biophysical Journal·2023Open Access
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Frequent Co-authors

Volker Kiessling(11), Binyong Liang(6), Jonathan M. Crane(5), Heedeok Hong(5), Jörg H. Kleinschmidt(5), Sung‐Tae Yang(4), Ashish Arora(4), Judith M. White(4), John H. Bushweller(3), Harden M. McConnell(2), Suren A. Tatulian(2), Sammy Frey(2), Xing Han(2), David S. Cafiso(2), Alex J.B. Kreutzberger(2), Reinhard Jahn(2), Michael Wagner(2), Alexander Stein(2), Dennis Rinehart(2), Gábor Szabó(2)