David S. Cafiso

University of Virginia — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

56h-index8.6kcitations278works10.02yr avg
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Research Topics

Lipid Membrane Structure and Behavior(110), Electron Spin Resonance Studies(75), Cellular transport and secretion(58), Advanced NMR Techniques and Applications(24), Photoreceptor and optogenetics research(23)

Publications278 total

Intermediate steps in the formation of neuronal SNARE complexes
Journal of Biological Chemistry·2024· 7 citedOpen Access
Unlocking Biradical Character in Diborepins
Journal of the American Chemical Society·2024· 23 cited
Ca2+-mediated synaptotagmin C2 domain binding to target membranes changes the physical properties of the lipid bilayer
Biophysical Journal·2024
Wayne Hubbell and the Path to Site-Directed Spin Labeling
Applied Magnetic Resonance·2023Open Access
A disulfide chaperone knockout facilitates spin labeling and pulse <scp>EPR</scp> spectroscopy of outer membrane transporters
Protein Science·2023· 2 citedOpen Access
Comparing different fluorescent probes to quantify lipid order alterations during Ca2+ mediated synaptotagmin C2 domain binding to membranes
Biophysical Journal·2023
Complexin-1 and synaptotagmin-1 compete for binding sites on membranes containing PtdInsP2
Biophysical Journal·2022· 8 citedOpen Access
Structural intermediates observed only in intact Escherichia coli indicate a mechanism for TonB-dependent transport
eLife·2021· 25 citedOpen Access
Author response: Structural intermediates observed only in intact Escherichia coli indicate a mechanism for TonB-dependent transport
2021Open Access
The Structure of the Coiled-Coil Domain of Ndel1 and the Basis of Its Interaction with Lis1, the Causal Protein of Miller-Dieker Lissencephaly
UNC Libraries·2021Open Access
Structural intermediates observed only in intact <i>Escherichia coli</i> indicate a mechanism for TonB-dependent transport
2021Open Access
Conserved arginine residues in synaptotagmin 1 regulate fusion pore expansion through membrane contact
Nature Communications·2021· 35 citedOpen Access
Disulfide Chaperone Knockouts Facilitate Double Spin Labelling of an Outer Membrane Transporter For in Vitro EPR Studies
Biophysical Journal·2021Open Access
Ebola Virus Glycoprotein Interacts with Cholesterol to Enhance Membrane Fusion and Cell Entry
Biophysical Journal·2021· 2 citedOpen Access
Triggering Fusion and Expanding the Fusion Pore: Dual Roles for the Second C2 Domain of Synaptotagmin 1
Biophysical Journal·2021Open Access
Ebola virus glycoprotein interacts with cholesterol to enhance membrane fusion and cell entry
Nature Structural & Molecular Biology·2021· 57 citedOpen Access
Conserved Arginine Residues in Synaptotagmin 1 Regulate Fusion Pore Expansion Through Membrane Contact
2020· 2 citedOpen Access
Native Cell Environment Constrains Loop Structure in the Escherichia coli Cobalamin Transporter BtuB
Biophysical Journal·2020· 18 citedOpen Access
Evidence for the Supramolecular Organization of a Bacterial Outer-Membrane Protein from In Vivo Pulse Electron Paramagnetic Resonance Spectroscopy
Journal of the American Chemical Society·2020· 24 citedOpen Access
Partial Metal Ion Saturation of C2 Domains Primes Synaptotagmin 1-Membrane Interactions
Biophysical Journal·2020· 9 citedOpen Access
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Frequent Co-authors

Jeffrey F. Ellena(9), Dawn Z. Herrick(6), Lukas K. Tamm(5), Wayne L. Hubbell(5), Stuart McLaughlin(4), John H. Bushweller(3), Gail E. Fanucci(3), Jaison Jacob(3), Anne Hinderliter(3), Reinhard Jahn(3), April A. Frazier(3), Weiwei Kuo(3), Xing Han(2), Diana Murray(2), J.C. Franklin(2), Ángel Pérez-Lara(2), Christopher L. North(2), Melissa Barranger-Mathys(2), David A. Nyenhuis(2), Evžen Bouřa(2)