Weiwei Kuo

Hawaii Pacific University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

5h-index372citations13works2.02yr avg
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Research Topics

Cellular transport and secretion(6), Lipid Membrane Structure and Behavior(5), Protease and Inhibitor Mechanisms(2), Photoreceptor and optogenetics research(2), Magnesium in Health and Disease(2)

Publications13 total

Transient Receptor Potential Melastatin 7 (TRPM7) Ion Channel Inhibitors: Preliminary SAR and Conformational Studies of Xenicane Diterpenoids from the Hawaiian Soft Coral <i>Sarcothelia edmondsoni</i>
Journal of Natural Products·2024· 2 citedOpen Access
The conformational landscape of a serpin N-terminal subdomain facilitates folding and in-cell quality control
2023· 2 citedOpen Access
Rapid detection of active pharmaceutical ingredients in drug products collected at an international mail facility by a satellite laboratory using a “toolkit” consisting of a handheld Raman spectrometer, portable mass spectrometer and portable FT-IR spectrometer
Journal of Pharmaceutical and Biomedical Analysis·2022· 11 cited
Crystal Structure Of Human Il-1beta In Complex With Antibody Binding Fragment Of IgG26
2020
Folding in Pieces
Biophysical Journal·2017Open Access
Waixenicin A Inhibits Cell Proliferation through Magnesium-dependent Block of Transient Receptor Potential Melastatin 7 (TRPM7) Channels
Journal of Biological Chemistry·2011· 153 citedOpen Access
Phosphatidylinositol 4,5-Bisphosphate Alters Synaptotagmin 1 Membrane Docking and Drives Opposing Bilayers Closer Together
Biochemistry·2011· 61 cited
Structure and Function of Synaptotagmin 1 C2 Domains as Determined by Site-Directed Spin Labeling
Biophysical Journal·2011Open Access
Charged Residues that Control the Electrostatic Association of Synaptotagmin 1 C2AB with Membranes
Biophysical Journal·2011Open Access
Electrostatic Interaction of Synaptotagmin I with PIP2 Containing Membranes
Libra·2010Open Access
Solution and Membrane-Bound Conformations of the Tandem C2A and C2B Domains of Synaptotagmin 1: Evidence for Bilayer Bridging
Journal of Molecular Biology·2009· 64 citedOpen Access
The Calcium-Dependent and Calcium-Independent Membrane Binding of Synaptotagmin 1: Two Modes of C2B Binding
Journal of Molecular Biology·2009· 79 citedOpen Access
Effects of Calcium and PIP2 on the Membrane Binding of Synaptotagmin I
Biophysical Journal·2009Open Access

Frequent Co-authors

David S. Cafiso(6), Dawn Z. Herrick(5), Jeffrey F. Ellena(3), Guangmin Yao(2), Peter Pörzgen(2), Reinhold Penner(2), F. David Horgen(2), Andrea Fleig(2), Upneet Kaur(2), Lila M. Gierasch(2), Patrick L. Wintrode(2), Daniel Deredge(2), Anne Gershenson(2), Susanna Zierler(1), Zheng Zhang(1), Hao Huang(1), Charles D. Schwieters(1), Adam Lanzarotta(1), Sara E. Kern(1), JaCinta S. Batson(1)