David A. Nyenhuis

National Institutes of Health — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index403citations40works0.82yr avg
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Research Topics

Electron Spin Resonance Studies(10), Cellular transport and secretion(8), Porphyrin Metabolism and Disorders(7), Viral Infections and Outbreaks Research(5), HIV Research and Treatment(4)

Publications40 total

BPS2026 - UEVLD as a potential tool to study Tsg-101 and an application model for pseudocontact shift experiments
Biophysical Journal·2026
BPS2026 - Leveraging related proteins to gain new structural insights into the UEV domain of the ESCRT-I factor Tsg101
Biophysical Journal·2026
BPS2026 – Intermediates of dynamin-mediated membrane fission resolved using cryo-EM
Biophysical Journal·2026
NMR chemical shift assignment of UEV domain of ubiquitin-conjugating enzyme E2 variant 3 lactate dehydrogenase (UEVLD)
Biomolecular NMR Assignments·2025Open Access
Humanin variants aggregate to produce different fibril morphologies
Journal of Biological Chemistry·2025Open Access
BPS2025 - FIP200's claw domain functions as an anionic membrane tether
Biophysical Journal·2025
BPS2025 - Structural context of the UEV domain: Tsg101 and beyond
Biophysical Journal·2025
BPS2025 - Structural context of the UEV domain, Tsg101, and beyond
Biophysical Journal·2025
Tsg101 mimicry of canonical E2 enzymes underlies its role in ubiquitin signaling
Proceedings of the National Academy of Sciences·2024· 3 citedOpen Access
Identification of Amino Acid Residues Critical for the Interaction of Fibrin with N-Cadherin
Biochemistry·2024· 1 citedOpen Access
Tsg101 UEV Interaction with Nedd4 HECT Relieves E3 Ligase Auto-Inhibition, Promoting HIV-1 Assembly and CA-SP1 Maturation Cleavage
Viruses·2024· 3 citedOpen Access
Structural Relationships to Efficacy for Prazole‐Derived Antivirals
Advanced Science·2024· 4 citedOpen Access
Unraveling the binding modes of the FIP200 CLAW domain
Biophysical Journal·2024
Observation of pH-Dependent Residual Structure in the Pmel17 Repeat Domain and the Implication for Its Amyloid Formation
Biochemistry·2023· 4 citedOpen Access
Probing P(T/S)XP peptides for novel structural interactions with Tsg101 UEV
Biophysical Journal·2023Open Access
HECT domain interaction with ubiquitin binding sites on Tsg101-UEV controls HIV-1 egress, maturation, and infectivity
Journal of Biological Chemistry·2023· 5 citedOpen Access
Incorporation of residual chemical shift anisotropy into the treatment of 15N pseudocontact shifts for structural refinement
Journal of Magnetic Resonance·2022· 1 citedOpen Access
Structural intermediates observed only in intact Escherichia coli indicate a mechanism for TonB-dependent transport
eLife·2021· 25 citedOpen Access
Author response: Structural intermediates observed only in intact Escherichia coli indicate a mechanism for TonB-dependent transport
2021Open Access
Novel Tsg101 Binding Partners Regulate Viral L Domain Trafficking
Viruses·2021· 12 citedOpen Access
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Frequent Co-authors

David S. Cafiso(21), Nico Tjandra(17), Thushani D. Nilaweera(11), Sarah B. Nyenhuis(5), Elizabeth A. Nelson(5), Judith M. White(5), Lukas K. Tamm(5), Susan M. Watanabe(5), Carol A. Carter(4), Robert K. Nakamoto(4), Ángel Pérez-Lara(3), Anusa Thapa(3), Partho Halder(3), Kai Tittmann(3), Reinhard Jahn(3), Alex J.B. Kreutzberger(3), Volker Kiessling(3), Jinwoo Lee(3), Marie-Paule Strub(3), Michael Tietzel(2)