Jacquelyn Hanson

SQZ Biotech (United States) — United States

Medicine · Health Sciences

1h-index185citations13works0.02yr avg
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Research Topics

CAR-T cell therapy research(7), RNA Interference and Gene Delivery(4), CRISPR and Genetic Engineering(3), Microfluidic and Bio-sensing Technologies(2), Viral Infectious Diseases and Gene Expression in Insects(2)

Publications13 total

A next generation immune cell engineering platform to create multifunctional cells using a silicon membrane-based delivery system 4591
The Journal of Immunology·2025Open Access
1027 A silicon membrane-based approach to deliver circular RNAs and engineer CAR-Ts with durable expression of membrane bound IL-2 and IL-12
Regular and Young Investigator Award Abstracts·2025Open Access
1017 A next generation immune cell engineering platform to create multifunctional cells using a silicon membrane-based delivery system
Regular and Young Investigator Award Abstracts·2025Open Access
Abstract 3160: Silicon membrane technology enables novel live-cell assays for screening impermeable compounds prior to medchem optimization
Cancer Research·2025
Abstract 5862: Combining circular RNA and a silicon membrane-based cell engineering approach to create CAR-Ts with membrane bound IL-2 and IL-12
Cancer Research·2025
A Highly Versatile Platform for Multiplexed Cell Engineering for Cancer Immunotherapy and Stem Cell Therapy
Blood·2024Open Access
350 A platform for multiplexed RNA-based and genomic cell engineering for cancer immunotherapy
Regular and Young Investigator Award Abstracts·2024Open Access
Abstract B046: Enhanced immune cell engineering utilizing a novel, effective intracellular delivery method for introduction of diverse cargo types
Cancer Immunology Research·2024
A new benchtop system for simple and versatile introduction of macromolecules into human lymphocytes and CD34+ cells by microfluidic squeezing
The Journal of Immunology·2023Open Access
Non-Genotoxic Conditioning Approach for Autologous Hematopoietic Stem Cell Therapies through Transient mRNA Engineering Using Vector-Free Microfluidic Cell Squeeze® Technology
Blood·2022· 1 cited
Abstract 1445: Tumor-specific T cell engineering for enhanced effector function via microfluidic delivery of bioactive molecules
Clinical Research (Excluding Clinical Trials)·2019
Abstract 1445: Tumor-specific T cell engineering for enhanced effector function via microfluidic delivery of bioactive molecules
Cancer Research·2019
Cell engineering with microfluidic squeezing preserves functionality of primary immune cells in vivo
Proceedings of the National Academy of Sciences·2018· 184 citedOpen Access

Frequent Co-authors

Armon Sharei(12), Eleni Rogers(9), Zhihui Song(8), Steffen Hirsch(8), Darby Kreienberg(8), Andrew R. Barclay(8), Alain Larocque(7), Tia DiTommaso(3), Julie M. Cole(3), Luke Cassereau(3), Jonathan B. Gilbert(3), Howard Bernstein(3), Mathias Pawlak(3), Richard C. Conover(3), Devin Bridgen(2), Scott Loughhead(2), Roslyn Yi(2), Josh Bugge(2), Joshua Buggé(1), Brittany Stokes(1)