Tia DiTommaso

Raptamer Discovery Group (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index2.4kcitations31works0.82yr avg
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Research Topics

CRISPR and Genetic Engineering(9), Skin and Cellular Biology Research(6), CAR-T cell therapy research(5), Hair Growth and Disorders(4), RNA regulation and disease(4)

Publications29 total

ABO-101, a Novel Gene Editing Therapy for Primary Hyperoxaluria Type 1, Is Effective and Well Tolerated in Nonhuman Primates (NHPs) and Results in High-Fidelity Editing in Primary Hepatocytes
Journal of the American Society of Nephrology·2025
Structural basis for target DNA cleavage and guide RNA processing by CRISPR-Casλ2
Communications Biology·2025· 4 citedOpen Access
Structural basis for target DNA cleavage and guide RNA processing by CRISPR-Casλ2
2025Open Access
Development of ABO-101, a Novel Gene Editing Therapy for Primary Hyperoxaluria Type 1
Journal of the American Society of Nephrology·2024
Amputation Triggers Long-Range Epidermal Permeability Changes in Evolutionarily Distant Regenerative Organisms
2024Open Access
Engineered Cas12i2 is a versatile high-efficiency platform for therapeutic genome editing
Nature Communications·2022· 46 citedOpen Access
Abstract 1445: Tumor-specific T cell engineering for enhanced effector function via microfluidic delivery of bioactive molecules
Clinical Research (Excluding Clinical Trials)·2019
Abstract 1445: Tumor-specific T cell engineering for enhanced effector function via microfluidic delivery of bioactive molecules
Cancer Research·2019
A comparative study elucidating the substantial functional defects of electroporated T cells relative to a mechanical SQZ-based approach
Annals of Oncology·2018Open Access
Cell engineering with microfluidic squeezing preserves functionality of primary immune cells in vivo
Proceedings of the National Academy of Sciences·2018· 184 citedOpen Access
Abstract A55: Vector-free genome editing of immune cells for cell therapy
Cancer Immunology Research·2018
Systemic cell cycle activation is induced following complex tissue injury in axolotl
Developmental Biology·2017· 69 cited
Mouse models in cutaneous biology
Figshare·2017Open Access
Mouse models in cutaneous biology
Monash University·2017Open Access
A Tissue-Mapped Axolotl De Novo Transcriptome Enables Identification of Limb Regeneration Factors
Cell Reports·2017· 1.1k citedOpen Access
A Tissue-Mapped Axolotl De Novo Transcriptome Enables Identification of Limb Regeneration Factors
DSpace@MIT (Massachusetts Institute of Technology)·2017Open Access
Mouse models in cutaneous biology
Monash University·2017Open Access
INPP5E regulates phosphoinositide-dependent cilia transition zone function
The Journal of Cell Biology·2016· 119 citedOpen Access
Vector Free Genome Editing of Human CD34+ Cells for Cell Therapy
Blood·2016
573. Vector Free Genome Editing of Immune Cells for Cell Therapy
Molecular Therapy·2016· 2 citedOpen Access
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Frequent Co-authors

Ian Smyth(8), Howard Bernstein(7), Armon Sharei(7), Jessica L. Whited(5), Luke Cassereau(5), Anthony J. Garrity(5), Winston X. Yan(5), Joel Bateman(4), Jonathan B. Gilbert(4), Gabrielle Munoz(4), K.A. Johnson(3), Duygu Payzin‐Dogru(3), Tzu‐Hsing Kuo(3), Julie M. Cole(3), Joshua Buggé(3), Jacquelyn Hanson(3), Lynelle K. Jones(3), Fiona M. Watt(3), Alexa Ornstein(3), Lauren E. Alfonse(3)