Anthony J. Garrity

Raptamer Discovery Group (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

7h-index1.9kcitations17works2.22yr avg
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Research Topics

CRISPR and Genetic Engineering(7), Cell Image Analysis Techniques(7), Single-cell and spatial transcriptomics(5), RNA regulation and disease(3), RNA and protein synthesis mechanisms(2)

Publications17 total

ABO-101, a Novel Gene Editing Therapy for Primary Hyperoxaluria Type 1, Is Effective and Well Tolerated in Nonhuman Primates (NHPs) and Results in High-Fidelity Editing in Primary Hepatocytes
Journal of the American Society of Nephrology·2025
Structural basis for target DNA cleavage and guide RNA processing by CRISPR-Casλ2
Communications Biology·2025· 4 citedOpen Access
Initial Characterization of 12 New Subtypes and Variants of Type V CRISPR Systems
The CRISPR Journal·2025· 7 cited
Structural basis for target DNA cleavage and guide RNA processing by CRISPR-Casλ2
2025Open Access
Development of ABO-101, a Novel Gene Editing Therapy for Primary Hyperoxaluria Type 1
Journal of the American Society of Nephrology·2024
Engineered Cas12i2 is a versatile high-efficiency platform for therapeutic genome editing
Nature Communications·2022· 46 citedOpen Access
CloneSifter: enrichment of rare clones from heterogeneous cell populations
BMC Biology·2020· 26 citedOpen Access
Additional file 5 of CloneSifter: enrichment of rare clones from heterogeneous cell populations
Figshare·2020Open Access
Additional file 2 of CloneSifter: enrichment of rare clones from heterogeneous cell populations
Figshare·2020Open Access
Additional file 3 of CloneSifter: enrichment of rare clones from heterogeneous cell populations
Figshare·2020Open Access
Additional file 4 of CloneSifter: enrichment of rare clones from heterogeneous cell populations
Figshare·2020Open Access
Optical Pooled Screens in Human Cells
Cell·2019· 305 citedOpen Access
CloneRetriever: retrieval of rare clones from heterogeneous cell populations
2019· 2 cited
Functionally diverse type V CRISPR-Cas systems
Science·2018· 509 citedOpen Access
Pooled optical screens in human cells
2018· 15 citedOpen Access
Genetic and transcriptional evolution alters cancer cell line drug response
Nature·2018· 890 citedOpen Access
Lentiviral co-packaging mitigates the effects of intermolecular recombination and multiple integrations in pooled genetic screens
2018· 56 citedOpen Access

Frequent Co-authors

David Feldman(9), Paul C. Blainey(9), Ryan O’Rourke(7), Pratiti Bandopadhayay(7), Rameen Beroukhim(7), Winston X. Yan(7), FuNien Tsai(6), Lisa Brenan(6), Patricia Ho(6), Elizabeth M. Gonzalez(6), Silvana Konermann(6), Cory M. Johannessen(6), Lauren E. Alfonse(5), David R. Cheng(5), David Scott(5), Tia DiTommaso(5), Gabrielle Munoz(4), Alexa Ornstein(4), Avtar Singh(3), Pratyusha Hunnewell(2)