Aoife Quinlan

University College Cork — Ireland

Immunology and Microbiology · Life Sciences

13h-index650citations23works0.02yr avg
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Research Topics

Immune Response and Inflammation(5), Immune Cell Function and Interaction(5), IL-33, ST2, and ILC Pathways(5), Inflammatory Bowel Disease(4), RNA Interference and Gene Delivery(4)

Publications23 total

PEGylated cyclodextrins as novel siRNA nanosystems: Correlations between polyethylene glycol length and nanoparticle stability
International Journal of Pharmaceutics·2014· 51 cited
409 The Colonic Adherent-Invasive Escherichia coli Strain HM605 Induces Anti-Apoptotic Responses in Intestinal Epithelial Cells, Reduces Barrier Integrity and Worsens Experimental Colitis
Gastroenterology·2014Open Access
273 High Fat Feeding Alters Gut Microbiota and Protects Mice From Colitis and Colitis-Associated Colorectal Cancer
Gastroenterology·2014
Differential nanotoxicological and neuroinflammatory liabilities of non-viral vectors for RNA interference in the central nervous system
Biomaterials·2013· 38 citedOpen Access
Activation of liver X receptor suppresses the production of the IL-12 family of cytokines by blocking nuclear translocation of NF-κBp50
Innate Immunity·2013· 17 citedOpen Access
Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis
Nature Immunology·2013· 97 cited
Sa1818 Natural Killer Cells Contribute to Clearance of the Enteric Pathogen Citrobacter Rodentium Through Direct and Indirect Mechanisms
Gastroenterology·2013
Gene silencing of TNF-alpha in a murine model of acute colitis using a modified cyclodextrin delivery system
Journal of Controlled Release·2013· 73 cited
Natural killer cells protect mice from DSS-induced colitis by regulating neutrophil function via the NKG2A receptor
Mucosal Immunology·2013· 65 citedOpen Access
Natural Killer Cells Protect against Mucosal and Systemic Infection with the Enteric Pathogen Citrobacter rodentium
Infection and Immunity·2012· 58 citedOpen Access
In Vitro Investigations of the Efficacy of Cyclodextrin-siRNA Complexes Modified with Lipid-PEG-Octaarginine: Towards a Formulation Strategy for Non-viral Neuronal siRNA Delivery
Pharmaceutical Research·2012· 41 cited
The Sphingosine-1-Phosphate Analogue FTY720 Impairs Mucosal Immunity and Clearance of the Enteric Pathogen Citrobacter rodentium
Infection and Immunity·2012· 27 citedOpen Access
Sa1870 MiR-375 is a Key Regulator of Intestinal Homeostasis in Response to Inflammatory Stress
Gastroenterology·2012· 2 citedOpen Access
1109 NK Cells Protect Mice During Acute Experimental Colitis by Regulating Neutrophil Function via NKG2A-dependent Mechanisms
Gastroenterology·2012Open Access
MiR-146a Negatively Regulates IL-17A Inflammatory Response and is Elevated in Intestinal Epithelial Cells From Inflammatory Bowel Disease (IBD) Patients
Gastroenterology·2011· 1 citedOpen Access
The Immunomodulatory Drug FTY720 Prevents Clearance of Citrobacter rodentium Infection in Mice
Gastroenterology·2011
Technical Advance: Function and efficacy of an α4-integrin antagonist using bioluminescence imaging to detect leukocyte trafficking in murine experimental colitis
Journal of Leukocyte Biology·2010· 16 cited
Use of bioluminescence imaging to track neutrophil migration and its inhibition in experimental colitis
Clinical & Experimental Immunology·2010· 30 citedOpen Access
Induction and Activation of Adaptive Immune Populations During Acute and Chronic Phases of a Murine Model of Experimental Colitis
Digestive Diseases and Sciences·2010· 109 cited
T1718 Natural Killer Cell Responses in Both Acute and Chronic Phases of a Murine Model of Experimental Colitis
Gastroenterology·2009
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Frequent Co-authors

Silvia Melgar(18), Fergus Shanahan(17), Kenneth Nally(14), Gráinne Hurley(12), C. Murphy(11), Lindsay J. Hall(10), Gerard M. Moloney(5), Julien Ogier(4), Caitríona M. O’Driscoll(4), John MacSharry(4), Émilie Faivre(3), Trevor Darby(3), Raphael Darcy(3), John F. Cryan(3), Paul N. Moynagh(2), Joanna McCarthy(2), Bruno M.D.C. Godinho(2), Peter G. McLean(2), Mahmoud Ali(2), Monica Ambrose(2)